[HTML][HTML] Gastric cancer in the era of precision medicine

X Liu, SJ Meltzer - Cellular and molecular gastroenterology and …, 2017 - Elsevier
Gastric cancer (GC) remains the third most common cause of cancer death worldwide, with
limited therapeutic strategies available. With the advent of next-generation sequencing and …

[HTML][HTML] Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

I Riquelme, K Saavedra, JA Espinoza, H Weber… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third leading cause of cancer mortality worldwide. Although
surgical resection is a potentially curative approach for localized cases of GC, most cases of …

[HTML][HTML] Clinical implementation of precision medicine in gastric cancer

J Jeon, JH Cheong - Journal of gastric cancer, 2019 - ncbi.nlm.nih.gov
Gastric cancer (GC) is one of the deadliest malignancies in the world. Currently, clinical
treatment decisions are mostly made based on the extent of the tumor and its anatomy, such …

Gastric cancer—molecular and clinical dimensions

R Wadhwa, S Song, JS Lee, Y Yao, Q Wei… - Nature reviews Clinical …, 2013 - nature.com
Gastric cancer imposes a considerable health burden around the globe despite its declining
incidence. The disease is often diagnosed in advanced stages and is associated with a poor …

[HTML][HTML] Targeted therapy in gastric cancer: personalizing cancer treatment based on patient genome

SM Lim, JY Lim, JY Cho - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Gastric cancer is the second leading cause of cancer-related deaths worldwide.
Conventional cytotoxic chemotherapy has limited efficacy for metastatic gastric cancer, with …

[HTML][HTML] Molecular targets for gastric cancer treatment and future perspectives from a clinical and translational point of view

J Koerfer, F Lordick, UT Hacker - Cancers, 2021 - mdpi.com
Simple Summary During the last several years, gastric cancer has been extensively studied
on the molecular level and distinct molecular subtypes have been defined accordingly …

[HTML][HTML] Gastric cancer genomics: advances and future directions

BW Katona, AK Rustgi - Cellular and molecular gastroenterology and …, 2017 - Elsevier
Advancement in the field of cancer genomics is revolutionizing the molecular
characterization of a wide variety of different cancers. Recent application of large-scale, next …

Molecular pathogenesis, targeted therapies, and future perspectives for gastric cancer

Y Zeng, RU Jin - Seminars in cancer biology, 2022 - Elsevier
Gastric cancer is a major source of global cancer mortality with limited treatment options and
poor patient survival. As our molecular understanding of gastric cancer improves, we are …

[HTML][HTML] Emerging molecular classifications and therapeutic implications for gastric cancer

T Chen, XY Xu, PH Zhou - Chinese journal of cancer, 2016 - Springer
Gastric cancer (GC) is a highly aggressive and life-threatening malignancy. Even with
radical surgical removal and front-line chemotherapy, more than half of GCs locally relapse …

Defining treatment standards and novel insights into disease biology

EC Smyth, D Cunningham - Nature Reviews Clinical Oncology, 2013 - nature.com
Gastric cancer is a heterogeneous disease with almost one million new cases occurring
annually worldwide. The year 2012 saw important successes and failures in gastric cancer …