The endothelium is composed of a monolayer of endothelial cells, lining the interior surface
of blood and lymphatic vessels. Endothelial cells display important homeostatic functions …

Hypertension contributes significantly to worldwide cardiovascular morbidity and mortality.
Hypertension appears to have a complex association with endothelial dysfunction, a …

Endothelium plays a fundamental role in the cardiovascular system, forming an interface
between blood and adjacent tissues by regulating the vascular tone through the synthesis of …

Endothelial dysfunction is a common feature of hypertension, and it results from the
imbalanced release of endothelium-derived relaxing factors (EDRFs; in particular, nitric …

A large body of evidence indicates that patients with essential hypertension are
characterized by endothelial dysfunction mediated by an impaired NO availability secondary …

In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

Far from simply lining the inner surface of blood vessels, the cellular monolayer that
comprises the endothelium is a highly active organ that regulates vascular tone. In health …

Endothelial dysfunction: its role in hypertensive coronary d... : Current Opinion in Cardiology
Endothelial dysfunction: its role in hypertensive coronary disease : Current Opinion in Cardiology …

Endothelial dysfunction has been implicated as a key factor in the development of a wide
range of cardiovascular diseases, but its definition and mechanisms vary greatly between …

The endothelium is recognized as a major determinant of vascular physiology and
pathophysiology. Over the last few decades, a plethora of studies have implicated …