A large body of evidence indicates that patients with essential hypertension, and even more
those with complicated hypertension, are characterized by endothelial dysfunction …

Endothelial dysfunction (ED) in the setting of cardiovascular risk factors such as
hypercholesterolemia, hypertension, diabetes mellitus, chronic smoking as well as in …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Recent research on endothelial dysfunction supports its clinical significance in hypertension,
and has led to important insights into the pathophysiology of the disease. These …

Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …

Endothelial dysfunction is characterized by a reduction in nitric oxide generation or an
unbalanced distribution of the relaxing and contracting pressures produced by endothelial …

The endothelium plays important roles in modulating vascular tone by synthesizing and
releasing a variety of endothelium-derived relaxing factors, including vasodilator …

Endothelial dysfunction is considered as a universal non-specific link in the pathogenesis of
many diseases, primarily the cardiovascular system. This review is devoted to the discussion …

The vascular endothelium synthesizes and releases a spectrum of vasoactive substances
like nitric oxide (NO) and endothelin (ET). In hypertension, the delicate balance of …

Hypertension is a risk factor for other cardiovascular diseases and endothelial dysfunction
was found in humans as well as in various commonly employed animal experimental …