Background and Objectives Angiotensin converting enzyme inhibitor (ACEI) is known to be
effective in the prevention of left ventricular failure (LVF) after acute myocardial infarction …

Background Major classes of medical therapy for heart failure with reduced ejection fraction
(HFrEF) induce reverse remodeling. The revere remodeling response to sacubitril/valsartan …

Aims RESOLVD study patients were randomized to candesartan (C), enalapril (E), or C+ E.
Patients were later randomized to metoprolol CR (M) or placebo. Examine impact of C or E …

Background In patients with heart failure with reduced ejection fraction (HFrEF), treatment
with sacubitril–valsartan (S/V) may reverse left ventricular remodeling (rLVR). Whether this …

Background Patients with acute myocardial infarction (AMI) are usually treated with
angiotensin-converting enzyme inhibitors (ACEIs), or angiotensin receptor blockers (ARBs) …

Abstract Effects of angiotensin receptor/neprilysin inhibitors (ARNI) on ventricular
remodeling in patients with heart failure, especially heart failure with reduced ejection …

Objectives: The objective of the study was to evaluate the effect of an angiotensin receptor
blocker on left ventricular (LV) structure and function when added to prescribed heart failure …

Aims Although the beneficial effect of sacubitril/valsartan (SAC/VAL) compared to enalapril
was consistent across ischaemic cardiomyopathy (ICM) and non-ischaemic cardiomyopathy …

BACKGROUND: In the large-scale trial, Gruppo Italiano per lo Studio della Sopravvivenza
nell'Infarto Miocardico-3 (GISSI-3), patients receiving the combination of lisinopril and …

The physiological role of the renin angiotensin aldosterone system (RAAS) is to maintain the
integrity of the cardiovascular system. The effect of angiotensin II is mediated via the …