Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

D Kavvadias, G Scherer, F Cheung, G Errington… - Biomarkers, 2009 - Taylor & Francis
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine

D Kavvadias, G Scherer, M Urban, F Cheung… - … of Chromatography B, 2009 - Elsevier
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N-nitrosonornicotine (NNN), N-nitrosoanabasine (NAB) and N …

Tobacco-specific nitrosamines (NNAL, NNN, NAT, and NAB) exposures in the US Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

B Xia, BC Blount, T Guillot, C Brosius… - Nicotine and …, 2021 - academic.oup.com
Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

Formation and analysis of tobacco-specific N-nitrosamines

KD Brunnemann, B Prokopczyk… - Tobacco-Specific N …, 2017 - api.taylorfrancis.com
Chemical-analytical studies during the past 4 years led to several new observa tions on the
formation of tobacco-specific A-nitrosamines (TSNA) and their occurrence in smokeless …

Investigation of exposure biomarkers in human plasma following differing levels of tobacco-specific N-nitrosamines and nicotine in cigarette smoke

J Zhang, X Liu, B Shi, Z Yang, Y Luo, T Xu, D Liu… - Environmental …, 2022 - Elsevier
Tobacco-specific N-nitrosamines (TSNAs) are strong carcinogens widely found in tobacco
products, environmental tobacco smoke, lake, and wastewater. The main objective of this …

Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Assessment of tobacco specific nitrosamines (TSNAs) in oral fluid as biomarkers of cancer risk: A population-based study

R Pérez-Ortuño, JM Martínez-Sánchez, M Fu… - Environmental …, 2016 - Elsevier
Background Smoke-free laws are expected to reduce smoking habits and exposure to
secondhand smoke. The objective of this study was the measurement of tobacco specific …

TSNA exposure: levels of NNAL among Canadian tobacco users

CD Czoli, D Hammond - Nicotine & Tobacco Research, 2015 - academic.oup.com
Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …

Tobacco-Specific Nitrosamines and Their Pyridine-N-glucuronides in the Urine of Smokers and Smokeless Tobacco Users

I Stepanov, SS Hecht - Cancer Epidemiology Biomarkers & Prevention, 2005 - AACR
Tobacco-specific nitrosamines are believed to play a significant role as causes of cancer in
people who use tobacco products. Whereas the uptake of one tobacco-specific nitrosamine …

Quantification of four tobacco-specific nitrosamines in cigarette filter tips using liquid chromatography-tandem mass spectrometry

PM Clayton, A Cunningham, JDH Van Heemst - Analytical methods, 2010 - pubs.rsc.org
Tobacco-specific N-nitrosamines (TSNA) have been suggested by some scientists to play an
important role in tobacco smoke carcinogenesis. We have developed and validated an LC …