The tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
(NNAL) is a valuable biomarker for human exposure to the carcinogenic nitrosamine 4 …

Tobacco use constitutes a leading cause of mortality and morbidity worldwide. Tobacco-
specific nitrosamines (TSNAs) are an important class of biomarkers for tobacco carcinogen …

(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronides (sum of which is
denoted as total NNAL) are metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone …

Tobacco-specific nonvolatile N-nitrosamines in tobacco and in fresh mainstream and
sidestream smoke of cigarettes and cigars were quantitatively determined with a thermal …

An improved liquid chromatography tandem mass spectrometry (LC− MS/MS) method has
been developed for the determination of tobacco specific nitrosamines (TSNA). It utilizes four …

A heart‐cutting two dimensional liquid chromatography coupled with tandem mass
spectrometry method was developed for the analysis of tobacco‐specific N‐nitrosamines …

A specific and sensitive method was developed and validated to quantitatively analyze four
tobacco‐specific nitrosamines (TSNAs) in the particulate phase of mainstream cigarette …

In this work, we developed a system for the qualitative and quantitative analysis of four
tobacco-specific N-nitrosamines (TSNAs). This system was based on strong cation …

Tobacco-specific nitrosamines (TSNAs) are one of the most extensively and continually
studied classes of compounds found in tobacco and cigarette smoke. 1− 5 The TSNAs N …

Tobacco-specific nitrosamines (TSNA) are among the most important and abundant strongly
carcinogenic agents in unburned tobacco. It has been established that 4 …