The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity
A Gonzalez-Martin, BD Adams, M Lai, J Shepherd… - Nature …, 2016 - nature.com
Autoreactive B cells have critical roles in a large diversity of autoimmune diseases, but the
molecular pathways that control these cells remain poorly understood. We performed an in …
molecular pathways that control these cells remain poorly understood. We performed an in …
MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production
Y Mok, V Schwierzeck, DC Thomas… - The Journal of …, 2013 - journals.aai.org
MicroRNAs (MiRs) are small, noncoding RNAs that regulate gene expression
posttranscriptionally. In this study, we show that MiR-210 is induced by Oct-2, a key …
posttranscriptionally. In this study, we show that MiR-210 is induced by Oct-2, a key …
[HTML][HTML] Regulation of B-cell development and tolerance by different members of the miR-17∼ 92 family microRNAs
M Lai, A Gonzalez-Martin, AB Cooper, H Oda… - Nature …, 2016 - nature.com
The molecular mechanisms that regulate B-cell development and tolerance remain
incompletely understood. In this study, we identify a critical role for the miR-17∼ 92 …
incompletely understood. In this study, we identify a critical role for the miR-17∼ 92 …
Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse
TH Thai, HC Patterson, DH Pham… - Proceedings of the …, 2013 - National Acad Sciences
MicroRNA-155 (miR-155) regulates antibody responses and subsequent B-cell effector
functions to exogenous antigens. However, the role of miR-155 in systemic autoimmunity is …
functions to exogenous antigens. However, the role of miR-155 in systemic autoimmunity is …
The microRNA-212/132 cluster regulates B cell development by targeting Sox4
MicroRNAs have emerged as key regulators of B cell fate decisions and immune function.
Deregulation of several microRNAs in B cells leads to the development of autoimmune …
Deregulation of several microRNAs in B cells leads to the development of autoimmune …
Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice
BG Garchow, O Bartulos Encinas, YT Leung… - EMBO molecular …, 2011 - embopress.org
MicroRNAs (miRNAs) have been implicated in B cell lineage commitment, regulation of T
cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other …
cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other …
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
Inflammatory cytokines such as interleukin-17 (IL-17) promote inflammatory autoimmune
diseases. Although several microRNAs (miRNAs) have been shown to regulate autoimmune …
diseases. Although several microRNAs (miRNAs) have been shown to regulate autoimmune …
[HTML][HTML] MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
Mammalian noncoding microRNAs (miRNAs) are a class of gene regulators that have been
linked to immune system function. Here, we have investigated the role of miR-155 during an …
linked to immune system function. Here, we have investigated the role of miR-155 during an …
miR-155 indicates the fate of CD4+ T cells
L Chen, D Gao, Z Shao, Q Zheng, Q Yu - Immunology Letters, 2020 - Elsevier
MicroRNAs (miRNAs) are a class of short noncoding RNAs that regulate the translation of
target messenger RNA (mRNA) and consequently participate in a variety of biological …
target messenger RNA (mRNA) and consequently participate in a variety of biological …
[HTML][HTML] MicroRNA-155 influences B-cell function through PU. 1 in rheumatoid arthritis
S Alivernini, M Kurowska-Stolarska, B Tolusso… - Nature …, 2016 - nature.com
Abstract MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a
critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is …
critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is …