Neurotransmitter release occurs at active zones, which are specialized regions of the
presynaptic membrane. A dense collection of proteins at the active zone provides a platform …

Presynaptic active zones are synaptic vesicle release sites that play essential roles in the
function and pathology of mammalian neuromuscular junctions (NMJs). The molecular …

The neuromuscular junction (NMJ) plays a fundamental role in transferring information from
lower motor neuron to skeletal muscle to generate movement. It is also an experimentally …

Organization of presynaptic active zones is essential for development, plasticity, and
pathology of the nervous system. Recent studies indicate a trans-synaptic molecular …

As synapses form and mature the synaptic partners produce organizing molecules that
regulate each other's differentiation and ensure precise apposition of pre-and post-synaptic …

Neural circuits transmit information through synapses, and the efficiency of synaptic
transmission is closely related to the density of presynaptic active zones, where synaptic …

The neuromuscular junction (NMJ) displays considerable morphological plasticity as a result
of differences in activity level, as well as aging. This is true of both presynaptic and …

The neuromuscular junction (NMJ) is a unique, specialized chemical synapse that plays a
crucial role in transmitting and amplifying information from spinal motor neurons to skeletal …

Neuromuscular junctions (NMJs) are highly specialized synapses between lower motor
neurons and skeletal muscle fibers that play an essential role in the transmission of …

Abstract Erbin, Lano, Scribble, and Densin‐180 belong to LAP (leucine‐rich repeats and
PDZ domain) adaptor proteins involved in cell signaling pathways. Previously, we identified …