The search for the new selective and efficient inhibitors of carboxylesterases is a fairly
topical issue [1–4]. The enzymes of serine esterase subclass including acetylcholinesterase …

A series of phosphorylated flavonoids has been synthesized and evaluated in vitro for
inhibitory activity against carboxylesterase, acetylcholinesterase and butyrylcholinesterase …

Literature data and authors' own results on the role of serine hydrolases,
acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), as drug targets for treatment …

A number of new pyrazole and pyrimidine derivatives containing an allylmorpholine
fragment were obtained by reactions of chromone-containing allylmorpholines with 1, 2-and …

The classification, structure, and mechanism of catalytic action of carboxylesterase of
different origin are presented in the review. The prospects of carboxylesterases application …

BOLTNEVA et al. strate [15]. Measurements were performed in a Bio Rad Benchmark Plus
microplate spectrophotometer (France). Compounds were dissolved in DMSO; the …

We improved the synthetic procedure for 3-(2-arylhydrazono)-1, 1, 1-trifluro-3-
(phenylsulfonyl) propan-2-ones and established their structure. The study of their esterase …

Model phenanthrene seco-alkaloids (seco-glaucine and seco-boldine) obtained in the
medium of subcritical water (SBW) from plant aporphine alkaloids have been studied for the …

The considered serine esterases have a similar structure of the active sites and the same
mechanism of inhibition by OPIs, which consists in the phosphorylation of the serine residue …

Abstract Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) are two important
enzymes involved in the breakdown of the neurotransmitter acetylcholine and other choline …