To elucidate the mechanism of age-related changes in antioxidant and photoprotective
properties of human retinal pigment epithelium (RPE) melanosomes, the effect of in vitro …

Melanosomes of the retinal pigment epithelium (RPE) are relatively long‐lived organelles
that are theoretically susceptible to changes induced by exposure to visible light. Here …

Melanin is usually considered a photoprotective pigment and antioxidant agent, but it is
unclear how melanosomes protect pigmented cells against oxidative stress induced by light …

Aging may significantly modify antioxidant and photoprotective properties of melanin in
retinal pigment epithelium (RPE). Here, photoreactivity of melanosomes (MS), isolated from …

Melanosomes of the retinal pigment epithelium (RPE) are long lived organelles that may
undergo photobleaching with aging, which can diminish the antioxidant efficiency of …

Melanin in the long‐lived melanosomes of the retinal pigment epithelium (RPE) may
undergo photobleaching with aging, which appears to diminish the antioxidant function of …

It is known that during the process of aging, there is a significant decrease in the number of
melanosomes in the retinal pigment epithelium (RPE) cells in the human eye. Melanosomes …

Melanin in the human retinal pigment epithelium (RPE) is believed to play an important
photoprotective role. However, unlike in skin, melanosomes in the RPE are rather long‐lived …

The purpose of this study was to determine whether an age‐related increase in
photoreactivity of human retinal melanosomes (MS) can cause phototoxicity to retinal …

purpose. To determine the effects of human retinal pigment epithelial (RPE) cell pigment
granules on photosensitized and iron ion-mediated oxidation and the effect of the …