purpose. To determine the effects of human retinal pigment epithelial (RPE) cell pigment
granules on photosensitized and iron ion-mediated oxidation and the effect of the …

Even though melanin is commonly viewed as natural photoprotectant, the pigment
demonstrates residual photoreactivity, which under certain conditions could contribute to …

Purpose Isolated melanosomes are known to have antioxidant properties but whether the
granules perform an antioxidant function within cells is unclear. The aim of this study was to …

Oxidative destruction of the natural pigment melanin leads to a decrease in its concentration
in the cell, a decrease of antioxidant properties and the accumulation of products that exhibit …

With aging, retinal pigment epithelium melanosomes, by fusion with the age pigment
lipofuscin, form complex granules called melanolipofuscin. Lipofuscin granules may contain …

purpose. To determine whether aging is accompanied by changes in aerobic photoreactivity
of retinal pigment epithelial (RPE) melanosomes isolated from human donors of different …

The pigment melanin has antioxidant properties that could theoretically reduce oxidative
damage to the retinal pigment epithelium (RPE), perhaps protecting against retinal diseases …

The retinal pigment epithelium (RPE), which ensures the normal functioning of the neural
retina, is a pigmented single-cell layer that separates the retina from the Bruch's membrane …

Although photodegradation of the retinal pigment epithelium (RPE) melanin may contribute
to the etiology of age‐related macular degeneration, the molecular mechanisms of this …

The effect of continuous UV radiation and hydrogen peroxide on destruction and antioxidant
properties of synthetic DOPA-melanin (prepared by oxidation of 3, 4 …