Cultured retinal pigment epithelium (RPE) cells can phagocytize large foreign particles.
Heterogeneous melanin aggregates from Sepia officinalis, a species of cuttlefish, were fed …

In an attempt to determine the factors involved in ocular pigment variation, the eyes of pallid
mice (C57BL/6J–Pa/Pa), and those of littermate black mice (C57BL/6J–+/Pa) were …

Short wavelength visible light is viewed as the main agent responsible for oxidative
modification of melanin in the human retinal pigment epithelium (RPE). The aim of this …

Purpose: Light damage is implicated in the pathophysiology of Age-Related Macular
Degeneration (AMD). Population studies have shown a lower incidence of AMD in black …

Melanosomes from retinal pigmented epithelium readily inhibit photooxidation of lipids. This
effect is due to both passive screening of light and chemical interaction of melanosomes with …

Melanosomes were isolated from the retinal pigment epithelium (RPE), iris and choroid of
mature (age> 2 years) and newborn (age< 1 week) bovine eyes. Scanning electron …

Purpose.: The aim of this study was to investigate the autofluorescence (AF) of the RPE with
two-photon microscopy (TPM) and fluorescence lifetime imaging (FLIM) under normal and …

A novel approach to photoemission electron microscopy is used to enable the first direct
measurement of the absorption coefficient from intact melanosomes isolated from bovine …

Melanin, particularly eumelanin, is commonly viewed as an efficient antioxidant and
photoprotective pigment. Nonetheless, the ability of melanin to photogenerate reactive …

Visible light can induce the generation of singlet oxygen and can cause oxidative stress,
especially in melanocytes due to melanin photosensitization. Currently, there is no organic …