[HTML][HTML] The key role of DNA methylation and histone acetylation in epigenetics of atherosclerosis

HT Lee, S Oh, H Yoo, YW Kwon - Journal of lipid and …, 2020 - ncbi.nlm.nih.gov
Atherosclerosis, which is the most common chronic disease of the coronary artery,
constitutes a vascular pathology induced by inflammation and plaque accumulation within …

Aberrant DNA methylation in the pathogenesis of atherosclerosis

Z Hai, W Zuo - Clinica Chimica Acta, 2016 - Elsevier
Atherosclerosis, a multifactorial disease of large-and intermediate-sized arteries, is
characterized by the accumulation of lipids and the proliferation of arterial smooth muscle …

DNA methylation processes in atherosclerotic plaque

E Aavik, M Babu, S Ylä-Herttuala - Atherosclerosis, 2019 - Elsevier
Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over
100 years and novel molecular level mechanisms in the pathophysiology are still …

Epigenetic reprogramming in atherosclerosis

V Grimaldi, MT Vietri, C Schiano, A Picascia… - Current atherosclerosis …, 2015 - Springer
Recent data support the involvement of epigenetic alterations in the pathogenesis of
atherosclerosis. The most widely investigated epigenetic mechanism is DNA methylation …

DNA methylation abnormalities in atherosclerosis

S Tabaei, SS Tabaee - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Atherosclerosis is a complex disease with involvement of intermediate-, large-sized arteries.
Atherosclerosis is characterized by the accumulation of vascular lipids, immune system …

Epigenetics of atherosclerosis: emerging mechanisms and methods

N Khyzha, A Alizada, MD Wilson, JE Fish - Trends in molecular medicine, 2017 - cell.com
Atherosclerosis is a vascular pathology characterized by inflammation and plaque build-up
within arterial vessel walls. Vessel occlusion, often occurring after plaque rupture, can result …

Histone methylation and vascular biology

X Wei, X Yi, XH Zhu, DS Jiang - Clinical epigenetics, 2020 - Springer
The vasculature not only transports oxygenated blood, metabolites, and waste products but
also serves as a conduit for hormonal communication between distant tissues. Therefore, it …

DNA methylation, smooth muscle cells, and atherogenesis

MO Hiltunen, S Ylä-Herttuala - Arteriosclerosis, thrombosis, and …, 2003 - Am Heart Assoc
DNA methylation is a form of epigenetic modification of the genome that can regulate gene
expression. Hypermethylation of CpG islands in the promoter areas leads to decreased …

Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease

D Pons, FR de Vries, PJ van den Elsen… - European heart …, 2009 - academic.oup.com
Significant progress has been made in the clinical management of a variety of
cardiovascular diseases. Nevertheless, the therapeutic efficacy of the current treatment …

Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics

S Xu, D Kamato, PJ Little, S Nakagawa… - Pharmacology & …, 2019 - Elsevier
Atherosclerosis, the principal cause of cardiovascular death worldwide, is a pathological
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …