Brucella central carbon metabolism: an update

T Barbier, A Zúñiga-Ripa, S Moussa… - Critical reviews in …, 2018 - Taylor & Francis
The brucellae are facultative intracellular pathogens causing brucellosis, an important
zoonosis. Here, we review the nutritional, genetic, proteomic and transcriptomic studies on …

Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1, 6-bisphosphatases for full virulence in laboratory …

A Zúñiga-Ripa, T Barbier, R Conde-Álvarez… - Journal of …, 2014 - Am Soc Microbiol
The brucellae are the etiological agents of brucellosis, a worldwide-distributed zoonosis.
These bacteria are facultative intracellular parasites and thus are able to adjust their …

Brucella, nitrogen and virulence

S Ronneau, S Moussa, T Barbier… - Critical reviews in …, 2016 - Taylor & Francis
The brucellae are α-Proteobacteria causing brucellosis, an important zoonosis. Although
multiplying in endoplasmic reticulum-derived vacuoles, they cause no cell death, suggesting …

[HTML][HTML] Brucella adaptation and survival at the crossroad of metabolism and virulence

T Barbier, C Nicolas, JJ Letesson - FEBS letters, 2011 - Elsevier
“In vivo” bacterial nutrition, ie the nature of the metabolic network and substrate (s) used by
bacteria within their host, is a fundamental aspect of pathogenic or symbiotic lifestyles. A …

Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway

A Machelart, K Willemart… - Proceedings of the …, 2020 - National Acad Sciences
Mechanistic understanding of the factors that govern host tropism remains incompletely
understood for most pathogens. Brucella species, which are capable of infecting a wide …

[HTML][HTML] The Fast-Growing Brucella suis Biovar 5 Depends on Phosphoenolpyruvate Carboxykinase and Pyruvate Phosphate Dikinase but Not on Fbp and GlpX …

A Zúñiga-Ripa, T Barbier, L Lázaro-Antón… - Frontiers in …, 2018 - frontiersin.org
Bacteria of the genus Brucella infect a range of vertebrates causing a worldwide extended
zoonosis. The best-characterized brucellae infect domestic livestock, behaving as stealthy …

[HTML][HTML] Brucella Genital Tropism: What's on the Menu

JJ Letesson, T Barbier, A Zuniga-Ripa… - Frontiers in …, 2017 - frontiersin.org
If things such as Tripadvisor web-site or Foursquare apps existed for bacteria, for sure, to the
question “What is the best place to eat near me?” or “Where can I find my favorite food?” …

Whole-genome analyses of speciation events in pathogenic Brucellae

PSG Chain, DJ Comerci, ME Tolmasky… - Infection and …, 2005 - Am Soc Microbiol
Despite their high DNA identity and a proposal to group classical Brucella species as
biovars of Brucella melitensis, the commonly recognized Brucella species can be …

Brucella abortus induces a Warburg shift in host metabolism that is linked to enhanced intracellular survival of the pathogen

DM Czyż, JW Willett, S Crosson - Journal of bacteriology, 2017 - Am Soc Microbiol
Intracellular bacterial pathogens exploit host cell resources to replicate and survive inside
the host. Targeting these host systems is one promising approach to developing novel …

The brucellae and their success as pathogens

H Guerra - Critical reviews in microbiology, 2007 - Taylor & Francis
Brucellae are tiny, aerobic, slow growing, catalase and oxidase positive Gram negative
coccobacilli or small rods, which may reach man through exposure to tissues of mammalian …