Disappearance of monosomy 7 in a patient with aplastic anemia after eltrombopag treatment

Y Uchibori, A Hangaishi, Y Kamoda, M Hirao… - …, 2020 - Taylor & Francis
We present the case of a patient with aplastic anemia (AA) who was treated with
eltrombopag. To the best of our knowledge, this is the first report of the disappearance of …

Eltrombopag as initial monotherapy for severe aplastic anemia—a case report

GM Rodgers, JA Gilreath - Annals of Hematology, 2018 - Springer
Dear Editor, Eltrombopag is a small molecule thrombopoietin-receptor agonist approved to
treat patients with acquired severe aplastic anemia (SAA) with an insufficient response to …

[引用][C] Therapy‐related chronic myelomonocytic leukemia with unique chromosomal abnormalities: Monosomy 7 and t (12; 17)(p13; q11. 2)

TH Oo, L Kenney - American journal of hematology, 2007 - Wiley Online Library
To the Editor: A 74-year-old man diagnosed with chronic lymphocytic leukemia was started
on darbepoetin alfa (Aranesp) at a dose of 1.5 μg/kg subcutaneously once every 2 weeks for …

Dysmegakaryopoiesis and Transient Mild Increase in Bone Marrow Blasts in Patients With Aplastic Anemia Treated With Eltrombopag May Be Signs of Hematologic …

A Matsuda, K Imada, N Obara, H Iida… - American Journal of …, 2022 - academic.oup.com
Objectives Eltrombopag, a thrombopoietin-receptor agonist, stimulates hematopoiesis in
patients with acquired aplastic anemia (AA). Cytomorphologic changes in bone marrow after …

[HTML][HTML] Use of eltrombopag in treatment programs for patients with aplastic anemia

EA Mikhailova, AV Luchkin, AV Abramova… - Russian journal of …, 2022 - htjournal.ru
Introduction. The use of thrombopoietin receptor agonists, especially eltrombopag, in the
treatment of aplastic anemia (AA) patients who did not respond to the previous …

Eltrombopag combined with cyclosporine may have an effect on very severe aplastic anemia

H Cheng, X Wang, D Zhou, J Cao, A Larochelle… - Annals of …, 2019 - Springer
A previously healthy 48-year-old female presented with a 4-month history of increased
symptomatic anemia and 2 weeks of heavy vaginal bleeding. She had no significant family …

Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

R Desmond, DM Townsley, B Dumitriu… - Blood, The Journal …, 2014 - ashpublications.org
About a quarter of patients with severe aplastic anemia remain pancytopenic despite
immunosuppressive therapy. We have previously demonstrated that eltrombopag has …

Transformation of severe aplastic anemia to myelodysplastic syndrome with monosomy 7 in a patient who achieved transfusion independence after …

K Takai, M Sanada - [Rinsho Ketsueki] The Japanese Journal of …, 2000 - europepmc.org
A 72-year-old woman was given a diagnosis of severe aplastic anemia, and treated with
anabolic steroid and cyclosporin A starting in October 1996. Because this treatment was …

Myelodysplastic syndrome with monosomy 7 following combination therapy with granulocyte colony-stimulating factor, cyclosporin A and danazole in an adult patient …

M Tsuzuki, M Okamoto, T Yamaguchi, T Ino… - [Rinsho Ketsueki] The …, 1997 - europepmc.org
We report a case of severe aplastic anemia (SAA) treated with granulocyte colony-
stimulating factor (G-CSF), cyclosporin A and danazole, in which myelodysplastic syndrome …

[HTML][HTML] Myeloid neoplasm gene somatic mutations in patients with severe aplastic anemia treated with eltrombopag and standard immunosuppression

DM Townsley, JN Cooper, T Winkler, P Scheinberg… - Blood, 2016 - Elsevier
The major complication of severe aplastic anemia is clonal evolution, defined as any new
cytogenetic abnormality or progression to MDS/AML, which occurs in about 15% of SAA …