Similar to other diseases, genetic and environmental factors play important roles not only for
the development of osteoporosis but also for how individuals respond to drug treatment. The …

Osteoporosis is a complicated and preventable disease with major morbidity complications
that affects millions of people. In the last 15 years, there have been numerous studies and …

Osteoporosis is a prevalent disease, particularly among postmenopausal women,
characterized by low bone mass and increased skeletal fragility. It is a complex disease …

Pharmacogenomics and pharmacogenetics are emerging interdisciplinary areas recently
defined, respectively as “the investigation of variations of DNA and RNA characteristics as …

The challenge of personalized medicine is to move away from the traditional 'one-size-fits-
all'pharmacology to genotype-based individualized therapies. As an individual's response to …

Osteoporosis is the most common and serious skeletal disorder of the elderly; it is
characterized by reduced bone mass and deterioration of bone microarchitecture, with an …

The possibility to predict the outcome of medical treatments, both in terms of efficacy and
development of adverse effects, is the main goal of modern personalized medicine. The …

Osteoporosis is a systemic skeletal disease characterised by low bone mass and
deterioration in the microstructure of bone tissue, which causes bone fragility and …

Drug response is known to be highly variable among treated patients and affected by many
factors, such as age, sex, ethnicity, concomitant diseases, and pharmacological therapy …

The increase in life expectancy has led to higher incidence of chronic diseases and cancer,
as well as degenerative disorders including osteoporosis. Osteoporosis is a common age …