SNPs, adipokynes and adiposity in children with asthma

ME Machado, LC Porto, MG Alves Galvão… - Journal of …, 2023 - Taylor & Francis
Objectives Asthma and obesity are complex disorders influenced by environmental and
genetic factors. We performed an integrative review of genetic polymorphisms and …

Body mass index, adipokines and insulin resistance in asthmatic children and adolescents

R Morishita, MC Franco, FI Suano-Souza, D Solé… - Journal of …, 2016 - Taylor & Francis
Objective: This study aimed to describe the body mass index, insulin resistance, levels of
adipokines and inflammatory markers in Brazilian asthmatic children and adolescents and to …

Asthma development partially linked to adiponectin and leptin in overweight children

HS BAEK, YD KIM, YS PARK, JH SHIN… - Pediatric Allergy …, 2010 - pesquisa.bvsalud.org
PURPOSE: The prevalence of asthma and obesity is increasing concomitantly, but the link
between asthma and obesity is unclear. We sought to address possible roles of leptin and …

Analyses of shared genetic factors between asthma and obesity in children

E Melén, BE Himes, JM Brehm, N Boutaoui… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Epidemiologic studies consistently show associations between asthma and
obesity. Shared genetics might account for this association. OBJECTIVE: We sought to …

[HTML][HTML] An overview of the obese-asthma phenotype in children

V Fainardi, L Passadore, M Labate, G Pisi… - International journal of …, 2022 - mdpi.com
Asthma is the most common chronic disease in childhood. Overweight and obesity are
included among the comorbidities considered in patients with difficult-to-treat asthma …

[HTML][HTML] Obesity-related biomarkers underlie a shared genetic architecture between childhood body mass index and childhood asthma

X Han, Z Zhu, Q Xiao, J Li, X Hong, X Wang… - Communications …, 2022 - nature.com
Obesity and asthma are both common diseases with high population burden worldwide.
Recent genetic association studies have shown that obesity is associated with asthma in …

Mediators linking obesity to childhood asthma

YC Chen, YT Huang, WH Pan… - Pediatric Allergy and …, 2022 - Wiley Online Library
Background Obesity and asthma are highly associated, but the mechanisms underlying the
association remain unknown. We examined five mediators linking obesity with childhood …

Mediating pathways from central obesity to childhood asthma: a population-based longitudinal study

AH Chih, YC Chen, YK Tu, KC Huang… - European …, 2016 - Eur Respiratory Soc
The mediating pathways linking obesity and asthma are largely unknown. We aimed to
investigate the mediating pathways and to search for the most prominent pathological …

The asthma–obesity link in childhood: open questions, complex evidence, a few answers only

PM Matricardi, C Grüber, U Wahn… - Clinical & Experimental …, 2007 - Wiley Online Library
Obesity and asthma are public health priorities in developed countries. Genes which may
contribute to the control of both conditions include those encoding for the β2‐adrenergic …

[HTML][HTML] Asthma and obesity in children

F Sansone, M Attanasi, S Di Pillo, F Chiarelli - Biomedicines, 2020 - mdpi.com
Asthma and obesity are two major chronic diseases in children and adolescents. Recent
scientific evidence points out a causative role of obesity in asthma predisposition. However …