[HTML][HTML] Malaria and tuberculosis as diseases of neglected populations: state of the art in chemotherapy and advances in the search for new drugs
RV de Araújo, SS Santos, LM Sanches… - Memórias do Instituto …, 2020 - SciELO Brasil
Malaria and tuberculosis are no longer considered to be neglected diseases by the World
Health Organization. However, both are huge challenges and public health problems in the …
Health Organization. However, both are huge challenges and public health problems in the …
[HTML][HTML] Challenges in the development of drugs for the treatment of tuberculosis
Tuberculosis infection is a serious human health threat and the early 21st century has seen
a remarkable increase in global tuberculosis activity. The pathogen responsible for …
a remarkable increase in global tuberculosis activity. The pathogen responsible for …
Host-directed therapies for malaria and tuberculosis: Common infection strategies and repurposed drugs
P Baindara, S Agrawal, OL Franco - Expert Review of Anti-infective …, 2022 - Taylor & Francis
Introduction Malaria and tuberculosis are highly infectious diseases declared a global health
emergency by the World Health Organization, and together they account for more than 1.5 …
emergency by the World Health Organization, and together they account for more than 1.5 …
Antimalarial chemotherapy. Mechanisms of action, resistance, and new directions in drug discovery
AU Krettli - 2001 - SciELO Brasil
Malaria, one of the most ancient human diseases affects 400 million people yearly and
causes over 2.5 million deaths, mostly children, in sub-Saharan Africa, where the disease is …
causes over 2.5 million deaths, mostly children, in sub-Saharan Africa, where the disease is …
[HTML][HTML] New and repurposed drugs to treat multidrug-and extensively drug-resistant tuberculosis
Multidrug-resistant and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB,
respectively) continue to represent a challenge for clinicians and public health authorities …
respectively) continue to represent a challenge for clinicians and public health authorities …
Overcoming the prokaryote/eukaryote barrier in tuberculosis treatment: A prospect for the repurposing and use of antiparasitic drugs
JM Ezquerra-Aznárez, PE Almeida da Silva, JA Aínsa - Microorganisms, 2021 - mdpi.com
Antimicrobial resistance, the so-called silent pandemic, is pushing industry and academia to
find novel antimicrobial agents with new mechanisms of action in order to be active against …
find novel antimicrobial agents with new mechanisms of action in order to be active against …
Drugs against tuberculose: past, present and future
MVN Souza, TRA Vasconcelos - Química Nova, 2005 - SciELO Brasil
Approximately every minute, somewhere in the world four people die from tuberculosis (TB),
an infection of Mycobacterium tuberculosis with about 3 million deaths per year. In spite of …
an infection of Mycobacterium tuberculosis with about 3 million deaths per year. In spite of …
[HTML][HTML] The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated …
LA Basso, LHP Silva, AG Fett-Neto… - Memórias do Instituto …, 2005 - SciELO Brasil
The modern approach to the development of new chemical entities against complex
diseases, especially the neglected endemic diseases such as tuberculosis and malaria, is …
diseases, especially the neglected endemic diseases such as tuberculosis and malaria, is …
Tackling drug-resistant tuberculosis: current trends and approaches
R Tandon, M Nath - Mini Reviews in Medicinal Chemistry, 2017 - ingentaconnect.com
Tuberculosis is very much rampant in our society and accounts for a large number of deaths
annually. In spite of consistent efforts being made, the disease has not been curtailed yet …
annually. In spite of consistent efforts being made, the disease has not been curtailed yet …
Chemoresistance of Plasmodium falciparum and Plasmodium vivax parasites in Brazil: consequences on disease morbidity and control
BE Gama, MVG Lacerda, CT Daniel-Ribeiro… - Memorias do Instituto …, 2011 - SciELO Brasil
In Brazil, malaria still remains a clinically important febrile syndrome for local populations
and travelers, occurring mostly in the Amazon Basin. This review aims to report the main …
and travelers, occurring mostly in the Amazon Basin. This review aims to report the main …
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