Energy metabolism is significantly reprogrammed in many human cancers, and these
alterations confer many advantages to cancer cells, including the promotion of biosynthesis …

The pentose phosphate pathway (PPP), which branches from glycolysis at the first
committed step of glucose metabolism, is required for the synthesis of ribonucleotides and is …

The Pentose Phosphate Pathway (PPP) is one of the key metabolic pathways occurring in
living cells to produce energy and maintain cellular homeostasis. Cancer cells have higher …

During cancer progression, cancer cells are repeatedly exposed to metabolic stress
conditions in a resource-limited environment which they must escape. Increasing evidence …

Background: Tumorigenesis is associated with deregulation of nutritional requirements,
intermediary metabolites production, and microenvironment interactions. Unlike their normal …

Interest in cancer metabolism has increased in recent years. The pentose phosphate
pathway (PPP) is a major glucose catabolism pathway that directs glucose flux to its …

The pentose phosphate pathway, one of the main antioxidant cellular defense systems, has
been related for a long time almost exclusively to its role as a provider of reducing power …

The pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P),
produces NADPH and ribose 5-phosphate (R5P), and shunts carbons back to the glycolytic …

In recent years, there has been a revival of interest in metabolic changes of cancer cells as it
has been noticed that malignant transformation and metabolic reprogramming are closely …

Pentose phosphate pathways (PPP) are considered important in tumor proliferation
processes because of their role in supplying tumor cells with reduced NADP and carbons for …