Objectives The mechanisms that trigger flare in rheumatoid arthritis (RA) are unknown. In
murine arthritis models, dysfunctional lymph node (LN) drainage is associated with joint …

Proliferation of draining lymphatic vessels coupled with dynamic changes in lymph node
volume and flow are characteristic features in rheumatoid arthritis (RA). Furthermore …

Background Emerging research on the mechanisms of disease chronicity in experimental
arthritis has included a new focus on the draining lymph node (LN). Here, we combined …

Objective. To investigate the correlation between changes in radiological quantitative
assessment with changes in clinical and functional assessment from baseline to 3 months in …

Background The mechanisms by which only some rheumatoid arthritis (RA) patients
respond favorably to TNF blockade are still poorly characterized. The goal of this study was …

Draining lymph node (LN) enlargement has long been recognized as a hallmark of joint
inflammation in rheumatoid arthritis (RA) and can be quantified with magnetic resonance …

Objectives To identify the first time point of an MRI-verified response to certolizumab pegol
(CZP) therapy in patients with rheumatoid arthritis (RA). Methods Forty-one patients with …

Objectives We investigated whether local joint swelling recurs in the same joints over time in
patients with rheumatoid arthritis (RA) who are treated to target. Methods Patients with newly …

Objective To study the impact of swollen to tender joint count ratio (STR) and other baseline
characteristics on treatment response to a first course of anti–tumor necrosis factor (anti …

Background Rheumatoid arthritis (RA) treat-to-target (T2T) regimens often use the disease
activity score (28 joints) incorporating C-reactive protein (DAS28 CRP) as an outcome …