CNS nicotinic acetylcholine receptors are a family of ligand-gated cation channels that allow
the passage of calcium ions. They are structurally and functionally distinct from nicotinic …

Advances in our understanding of the structure, function and distribution of nicotinic
acetylcholine receptors in the CNS have provided the impetus for new studies examining the …

Advances in the understanding of the structure, function, and distribution of central nervous
system (CNS) nicotinic receptors has provided the impetus for new studies examining the …

Advances in the understanding of the structure, function, and distribution of central nervous
system (CNS) nicotinic receptors has provided the impetus for new studies examining the …

Nicotinic cholinergic agonists represent a relatively newly developing area for therapeutic
intervention in Alzheimer disease (AD) and related neurodegenerative dementias. Loss of …

Alzheimer's disease is a complex disorder affecting multiple neurotransmitters. In particular,
the degenerative progression is associated with loss within the cholinergic systems. It …

Nicotine and nicotinic agonists such as acetylcholine, methylcarbamyl choline, and cytisine
at nanomolar concentrations bind to a separate group of central nervous system (CNS) …

The acetylcholine nicotinic receptor is an ionic channel whose aperture is directly controlled
by acetylcholine. It is a key molecule in the chemical communication between nerve cells …

Activation of neuronal nicotinic acetylcholine receptors (nAChRs) has been shown to
maintain cognitive function following aging or the development of dementia. Nicotine and …

Neuronal nicotinic receptors are key molecules for signal transduction in a number of
neuronal pathways. They are widely distributed in the brain and are known to be involved in …