Digitalis is a plant-derived cardiac glycoside commonly used in the treatment of chronic
heart failure (CHF), atrial fibrillation, and reentrant supraventricular tachycardia. Direct …

Cardiac glycosides, also known as digitalis glycosides, have been used to treat heart
conditions in the medical world for at least 2,000 years. Known as a “natural medicine” to the …

Digoxin, the cardiac glycoside most frequently used in clinical practice in the United States,
can be given orally or intravenously and has an excretory half-life of 36 to 48 hours in …

The effects of concomitant drug therapy on the absorption, distribution, and elimination of
digoxin and digitoxin are reviewed. A number of agents can increase or decrease the …

The most important step in the management of toxicity due to any of the cardiac glycosides is
its recognition. Despite the development of an accurate clinical assay for serum levels of …

Digoxin usage has decreased in the treatment of congestive heart failure and atrial
fibrillation as a result of its inferiority to beta-adrenergic inhibitors and agents that interfere …

In recent years there has been a marked decrease in cardiac glycosides use in patients with
heart failure in sinus rhythm and atrial fibrillation. The results of published studies contradict …

Digitalis glycosides are among the oldest drugs used in cardiology. Nowadays, due to the
limited indications for their use (advanced heart failure, usually concomitant with atrial …