Background In the absence of definitive diagnosis, healthcare providers are likely to
prescribe empirical antibacterials to those who test negative for malaria. This problem is of …

Background Malaria incidence is in decline in many parts of SE Asia leading to a decreasing
proportion of febrile illness that is attributable to malaria. However in the absence of rapid …

Background Common causes of acute febrile illness in tropical countries have similar
symptoms, which often mimic those of dengue. Accurate clinical diagnosis can be difficult …

Intro Viruses that cause acute febrile illness (AFI) in sub-Saharan Africa (SSA) lead to a
spectrum of clinical disease from mild to life-threatening. Viral infection is often …

There is a paucity of data on the etiologies and outcomes of febrile illness in rural Sierra
Leone, especially in the Lassa-endemic district of Kenema. We conducted a retrospective …

Severe-febrile-illness (SFI) is a common cause of morbidity and mortality across sub-
Saharan Africa (SSA). The burden of SFI in SSA is currently unknown and its estimation is …

Background As international efforts to increase the coverage of artemisinin-based
combination therapy in public health sectors gather pace, concerns have been raised …

Background In 2010, WHO revised guidelines to recommend testing all suspected malaria
cases prior to treatment. Yet, evidence to assess programmes is largely derived from limited …

Abstract Background Acute febrile illnesses (AFIs) represent a major disease burden
globally; however, the paucity of reliable, rapid point-of-care testing makes their diagnosis …

Background Private sector availability and use of malaria rapid diagnostic tests (RDTs) lags
behind the public sector in Kenya. Increasing channels through which quality malaria …