Assessing the relationship between lung density and function with oxygen-enhanced magnetic resonance imaging in a mouse model of emphysema

M Zurek, L Sladen, E Johansson, M Olsson… - PLoS …, 2016 - journals.plos.org
Purpose A magnetic resonance imaging method is presented that allows for the
simultaneous assessment of oxygen delivery, oxygen uptake, and parenchymal density. The …

Functional proton MRI in emphysematous rats

A Bianchi, M Tibiletti, Å Kjørstad, G Birk… - Investigative …, 2015 - journals.lww.com
Objective To demonstrate the feasibility of proton magnetic resonance imaging (MRI)
ventilation–related maps in rodents for the evaluation of lung function in the presence of …

Longitudinal and noninvasive assessment of emphysema evolution in a murine model using proton MRI

M Zurek, L Boyer, P Caramelle… - Magnetic resonance …, 2012 - Wiley Online Library
Ultrashort echo time (550 μs) MR imaging was implemented to track the emphysema
development in mice lung challenged with elastase. Two parameters, namely, signal …

Measurement of MR signal and T2* in lung to characterize a tight skin mouse model of emphysema using single‐point imaging

LE Olsson, M Lindahl, PO Önnervik… - Journal of Magnetic …, 2007 - Wiley Online Library
Purpose To evaluate whether MRI signal and T2* measurements of lung tissue acquired at
ultrashort detection times (tds) can detect emphysematous changes in lungs. Materials and …

Impact of lung volume on MR signal intensity changes of the lung parenchyma

AA Bankier, CR O'Donnell, VM Mai… - Journal of Magnetic …, 2004 - Wiley Online Library
Purpose To test the hypothesis that, in magnetic resonance (MR) imaging of healthy
individuals, equal relative changes in lung volume cause equal relative changes in MR …

Thoracic magnetic resonance imaging for the evaluation of pulmonary emphysema

SM Lee, JB Seo, HJ Hwang, EY Kim… - Journal of Thoracic …, 2013 - journals.lww.com
Pulmonary emphysema is a pathologic condition characterized by permanently enlarged
airspaces distal to the terminal bronchiole with destruction of the alveolar walls. Functional …

Dynamic oxygen‐enhanced MRI reflects diffusing capacity of the lung

Y Ohno, H Hatabu, D Takenaka… - … in Medicine: An …, 2002 - Wiley Online Library
The purpose of this study was to demonstrate the feasibility of dynamic oxygen‐enhanced
MRI in a clinical setting. We hypothesized that dynamic oxygen enhancement can reflect the …

Validation of Noninvasive Morphological and Diffusion Imaging in Mouse Emphysema by Micro–Computed Tomography and Hyperpolarized 129Xe Magnetic …

S Tetsumoto, Y Takeda, H Imai, A Kimura… - American journal of …, 2013 - atsjournals.org
Animal disease models are pivotal in investigating the pathogenesis of emphysema and
developing novel drugs, but the modalities to evaluate murine emphysema models have …

Magnetic resonance lung function–a breakthrough for lung imaging and functional assessment? A phantom study and clinical trial

M Zapke, HG Topf, M Zenker, R Kuth, M Deimling… - Respiratory …, 2006 - Springer
Background Chronic lung diseases are a major issue in public health. A serial pulmonary
assessment using imaging techniques free of ionizing radiation and which provides early …

Pulmonary ventilation imaged by magnetic resonance: at the doorstep of clinical application

HU Kauczor, XJ Chen, EJR Van Beek… - European …, 2001 - Eur Respiratory Soc
Over the past few years, magnetic resonance imaging (MRI) has emerged as an important
instrument for functional ventilation imaging. The aim of this review is to summarize …