Interleukin-23: a new atherosclerosis target

W Liu, C Chang, H Hu, H Yang - Journal of interferon & cytokine …, 2018 - liebertpub.com
Accumulating evidence has shown that atherosclerosis is an inflammatory disease. The
pathogenesis of atherosclerosis has been confirmed to involve an imbalance in anti …

[HTML][HTML] Interleukin-22: a potential therapeutic target in atherosclerosis

JW Luo, Y Hu, J Liu, H Yang, P Huang - Molecular medicine, 2021 - Springer
Background Atherosclerosis is recognized as a chronic immuno-inflammatory disease that is
characterized by the accumulation of immune cells and lipids in the vascular wall. In this …

Effects of IL-22 on cardiovascular diseases

Y Che, Z Su, L Xia - International Immunopharmacology, 2020 - Elsevier
Abstract Interleukin-22 (IL-22), which belongs to the IL-10 family, is an alpha helix cytokine
specifically produced by many lymphocytes, such as Th1, Th17, Th22, ILCs, CD4+ and …

Emerging role of IL-17 in atherosclerosis

S Chen, TR Crother, M Arditi - Journal of innate immunity, 2010 - karger.com
Abstract The IL-23-IL-17 axis is emerging as a critical regulatory system that bridges the
innate and adaptive arms of the immune system. Th17 cells have been linked to the …

Interleukin-23: a key cytokine in inflammatory diseases

E Duvallet, L Semerano, E Assier, G Falgarone… - Annals of …, 2011 - Taylor & Francis
Abstract Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, p19
and p40. The p40 subunit is shared with IL-12. IL-23 and IL-12 have different receptors and …

The paradoxical role of IL-17 in atherosclerosis

F Gong, Z Liu, J Liu, P Zhou, Y Liu, X Lu - Cellular immunology, 2015 - Elsevier
Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune
responses. In recent years, CD4+ T cells (Th1, Th2, Treg, and Th17) have been increasingly …

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling

G Espígol-Frigolé, E Planas-Rigol, H Ohnuki… - Science …, 2016 - science.org
Interleukin-23 (IL-23), a heterodimeric cytokine composed of the unique p19 peptide (IL-
23p19) and a peptide called IL-12p40, which is shared with IL-12, is implicated in Crohn's …

The two faces of interleukin-17A in atherosclerosis

M Akhavanpoor, H Akhavanpoor… - Current Drug …, 2017 - ingentaconnect.com
A complex network of different cytokines and chemokines modulates atherosclerosis, a
chronic inflammatory disease. Interleukin-17A (IL-17A) is expressed by different leukocyte …

Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis

A Abbas, I Gregersen, S Holm, I Daissormont… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Interleukin (IL)-23 is a cytokine in the IL-12 family, mainly
produced by antigen-presenting cells with a central role in inflammation. We hypothesize …

IL-20 Is expressed in atherosclerosis plaques and promotes atherosclerosis in apolipoprotein E–deficient mice

WY Chen, BC Cheng, MJ Jiang, MY Hsieh… - … , and vascular biology, 2006 - Am Heart Assoc
Objective—Atherosclerosis is a chronic inflammatory disease with immune cell infiltration.
Various cytokines and chemokines have been characterized as pro-or antiatherogenic …