Graft-versus-host disease (GVHD)–associated dry eye disease is characterized by extensive
inflammatory destruction in the ocular surface and causes unbearable pain and visual …

Dry eye syndrome (DES) is one of the most common ocular diseases affecting nearly 10% of
the US population. Most of the currently available treatments are palliative, and few …

We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental
autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were …

Purpose: The objective of the study was to investigate efficacy and mechanisms of mouse
adipose-derived mesenchymal stem cell-derived exosomes (mADSC-Exos) in the …

Purpose: In this study, we aim to investigate whether mesenchymal stem cell (MSC)-derived
exosomes (MSC-Exos) could regulate hyperglycemia-induced retinal inflammation by …

Retinal ischemia-reperfusion injury (IRI) is one of the main pathogenic mechanisms of
glaucoma, which are largely unknown, including neuroinflammation and neuronal death in …

Mesenchymal stem cells (MSCs) were, due to their immunomodulatory and pro-angiogenic
characteristics, extensively explored as new therapeutic agents in cell-based therapy of …

Background Retinitis pigmentosa is a rod-cone degenerative disease that induces
irreversible vision loss. This study probed the protective capacity of mesenchymal stem cell …

The present study was set out to address the therapeutic efficacy of human adipose tissue
stem cells derived extracellular vesicles (hADSC-Evs) in a mouse model of dry eye disease …

Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is a major factor in the
pathogenesis of dry age-related macular degeneration (AMD). Although the therapeutic …