Objective. To evaluate the effect of maternally derived antibody on the immunogenicity and
reactogenicity of acellular (DTaP) or whole-cell (DTP) pertussis vaccine with diphtheria and …

BACKGROUND: Combined tetanus toxoid, reduced diphtheria toxoid, and acellular
pertussis vaccine (Tdap) boosters for adolescents are a new strategy to prevent pertussis …

Objectives: To compare the immunogenicities and reactogenicities of bicomponent
(B)(pertussis toxoid, filamentous hemagglutinin) and tricomponent (T)(pertussis toxoid …

The safety and immunogenicity of a booster dose of a new acellular pertussis component
diphtheria-tetanus toxoids-pertussis vaccine (DTaP) were compared with whole cell …

Adolescents, who comprise 14% of the US population, are historically resistant to receiving
health care. As a result, adolescents have low immunization rates and are becoming more …

Importance The United States has experienced a nationwide resurgence of pertussis since
the mid-1970s, despite high estimated vaccine coverage. Short-lived immunity induced by …

Background The effectiveness of diphtheria, tetanus, and acellular pertussis (DTaP)
vaccines wanes substantially after the 5 th dose given at ages 4–6 years, but has not been …

Despite the availability of a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis
(Tdap) vaccine in the United States since 2005, the vaccine remains underutilized and …

Background: Prelicensure clinical studies may not include sufficient numbers of subjects to
assess the potential for rare postvaccination adverse events. The aim of this postlicensure …

Background: In a previous study, we found that monovalent acellular pertussis (aP) vaccine
at birth and 1 month achieves higher IgG antibody (Ab) levels to pertussis toxoid (PT) …