Introduction Severe chronic obstructive pulmonary disease (COPD) is often associated with
secondary pulmonary hypertension (PH), which worsens prognosis. PH can be lowered by …

Objective Inhaled nitric oxide (NO) has been used for pulmonary vasodilation therapy in
patients with pulmonary hypertension. Inhaled NO for awake and ambulatory patients …

Background Inhaled nitric oxide (NO) has been shown to be a selective pulmonary
vasodilator in certain patients with primary pulmonary hypertension (PPH). Objectives The …

Background: Pulmonary hypertension is a frequent complication of severe chronic
obstructive pulmonary disease (COPD) and a major cause of morbidity and mortality in this …

BACKGROUND Inhalation of nitric oxide with oxygen could be a promising treatment in
patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension …

Pulmonary arterial hypertension (PAH) is a chronic, progressive disease of the pulmonary
vasculature with a high morbidity and mortality. Its pathobiology involves at least three …

Study objective To assess the effect of nitric oxide inhalation on pulmonary hemodynamics
and oxygenation in patients with COPD receiving long-term oxygen therapy (LTOT). Design …

Inhalation of nitric oxide (NO), an endoge‐neous vasodilator, was recently described to
reduce pulmonary vascular resistance, and to improve arterial oxygenation by selective …

Inhaled nitric oxide (iNO) has been shown to be a potent and selective vasodilator in
pulmonary arterial hypertension (PAH). However, the clinical experience in prolonged …

OBJECTIVES We sought to compare the responses of patients with pulmonary hypertension
from primary and secondary causes (PPH and SPH, respectively) to inhaled nitric oxide …