Rhein Reduces Fat Weight in db/db Mouse and Prevents Diet‐Induced Obesity in C57Bl/6 Mouse through the Inhibition of PPARγ Signaling

Y Zhang, S Fan, N Hu, M Gu, C Chu, Y Li, X Lu… - PPAR …, 2012 - Wiley Online Library
Rheum palmatum has been used most frequently in the weight‐reducing formulae in
traditional Chinese medicine. However, the components of Rheum palmatum that play the …

A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice

L Jin, M Wang, B Yang, L Ye, W Zhu, Q Zhang… - International …, 2023 - Elsevier
Background The prevalence of non-alcoholic fatty liver disease (NAFLD) has been deemed
a leading cause of end-stage liver disease. As a member of the mitogen-activated protein …

Magnesium isoglycyrrhizinate blocks fructose-induced hepatic NF-κB/NLRP3 inflammasome activation and lipid metabolism disorder

XJ Zhao, YZ Yang, YJ Zheng, SC Wang, HM Gu… - European journal of …, 2017 - Elsevier
Magnesium isoglycyrrhizinate as a hepatoprotective agent possesses immune modulation
and anti-inflammation, and treats liver diseases. But its effects on immunological …

Effect of Ruzu herbal bitters on the liver function and lipid profile parameters of Alloxan-induced diabetic rats

DC Obasi, VN Ogugua - Journal of Clinical and Experimental Hepatology, 2021 - Elsevier
Background Ruzu herbal bitters (RHB) is a polyherbal mixture produced in Nigeria indicated
for diabetes and other ailments. The consumers of the product testify of its efficacy, but there …

[HTML][HTML] Activation of AMPK entails the protective effect of royal jelly against high-fat-diet-induced hyperglycemia, hyperlipidemia, and non-alcoholic fatty liver disease …

AH Felemban, GM Alshammari, AEGA Yagoub… - Nutrients, 2023 - mdpi.com
This study examined the mechanism underlying the protective effect of royal jelly (RJ)
against high-fat-diet (HFD)-mediated non-alcoholic liver disease (NAFLD) in rats. Adult male …

Chrysin and its nanoliposome ameliorated non-alcoholic steatohepatitis via inhibiting TLR4 signalling pathway

H Liu, N Jiang, G Kuang, X Gong, J Hu… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives Non-alcoholic steatohepatitis (NASH) is a chronic liver disease histologically
characterized by liver steatosis, hepatocellular injury, inflammation and fibrosis, resulting in …

Saroglitazar deactivates the hepatic LPS/TLR4 signaling pathway and ameliorates adipocyte dysfunction in rats with high-fat emulsion/LPS model-induced non …

NF Hassan, SA Nada, A Hassan, MR El-Ansary… - Inflammation, 2019 - Springer
The most epidemic liver disorder non-alcoholic steatohepatitis (NASH) is characterized by
hepatic steatosis and inflammation with hepatocellular damage. Recently, it is predictable to …

Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice

MS Lee, D Kim, K Jo, JK Hwang - Biochemical and biophysical research …, 2010 - Elsevier
Nonalcoholic fatty liver disease, one of the most common causes of chronic liver disease, is
strongly associated with metabolic syndrome. Nordihydroguaiaretic acid (NDGA) has been …

Sheng‐Jiang Powder Ameliorates High Fat Diet Induced Nonalcoholic Fatty Liver Disease via Inhibiting Activation of Akt/mTOR/S6 Pathway in Rats

J Li, L Zhu, Y Zhang, H Chen, Y Miao… - Evidence‐Based …, 2018 - Wiley Online Library
Background and Aims. Nonalcoholic fatty liver disease (NAFLD) is an alarming public health
problem that directly contributes to increased prevalence of liver cirrhosis and hepatic cell …

Salidroside modulates insulin signaling in a rat model of nonalcoholic steatohepatitis

H Li, H Ying, A Hu, D Li, Y Hu - … ‐Based Complementary and …, 2017 - Wiley Online Library
A growing body of evidence has shown the beneficial effects of salidroside in cardiovascular
and metabolic diseases. This study aimed to evaluate the therapeutic effects of salidroside …