Virulence Characteristics and an Action Mode of Antibiotic Resistance in Multidrug-Resistant Pseudomonas aeruginosa
W Hwang, SS Yoon - Scientific reports, 2019 - nature.com
Pseudomonas aeruginosa displays intrinsic resistance to many antibiotics and known to
acquire actively genetic mutations for further resistance. In this study, we attempted to …
acquire actively genetic mutations for further resistance. In this study, we attempted to …
Transcriptome profiling of antimicrobial resistance in Pseudomonas aeruginosa
A Khaledi, M Schniederjans, S Pohl… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Emerging resistance to antimicrobials and the lack of new antibiotic drug candidates
underscore the need for optimization of current diagnostics and therapies to diminish the …
underscore the need for optimization of current diagnostics and therapies to diminish the …
A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas …
SJT Wardell, A Rehman, LW Martin… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide range of acute
and chronic infections. An increasing number of isolates have mutations that make them …
and chronic infections. An increasing number of isolates have mutations that make them …
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes
J Jeukens, I Kukavica-Ibrulj… - FEMS microbiology …, 2017 - academic.oup.com
Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …
The Versatile Mutational Resistome of Pseudomonas aeruginosa
C López-Causapé, G Cabot… - Frontiers in …, 2018 - frontiersin.org
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for
developing antimicrobial resistance to nearly all available antipseudomonal agents through …
developing antimicrobial resistance to nearly all available antipseudomonal agents through …
Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning‐enabled molecular diagnostics
A Khaledi, A Weimann, M Schniederjans… - EMBO molecular …, 2020 - embopress.org
Limited therapy options due to antibiotic resistance underscore the need for optimization of
current diagnostics. In some bacterial species, antimicrobial resistance can be …
current diagnostics. In some bacterial species, antimicrobial resistance can be …
Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas …
J Botelho, L Tüffers, J Fuss, F Buchholz, C Utpatel… - …, 2023 - thelancet.com
Background Pseudomonas aeruginosa is an opportunistic pathogen consisting of three
phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific …
phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific …
Next generation sequencing reveals the antibiotic resistant variants in the genome of Pseudomonas aeruginosa
Rapid progress in next generation sequencing and allied computational tools have aided in
identification of single nucleotide variants in genomes of several organisms. In the present …
identification of single nucleotide variants in genomes of several organisms. In the present …
Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosa
A Dötsch, T Becker, C Pommerenke… - Antimicrobial agents …, 2009 - Am Soc Microbiol
The emergence of antimicrobial drug resistance is of enormous public concern due to the
increased risk of delayed treatment of infections, the increased length of hospital stays, the …
increased risk of delayed treatment of infections, the increased length of hospital stays, the …
The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility
VN Kos, M Déraspe, RE McLaughlin… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Many clinical isolates of Pseudomonas aeruginosa cause infections that are difficult to
eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of …
eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of …
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