Current and emerging therapies in osteoporosis

A Buchman, A DeSantis - Expert Opinion on Pharmacotherapy, 2002 - Taylor & Francis
Osteoporosis is a systemic skeletal disorder leading to decreased bone mineralisation and a
propensity for fracture. The disease affects millions of people and is a source of significant …

Targeting fundamental aging mechanisms to treat osteoporosis

J Feehan, A Al Saedi, G Duque - Expert Opinion on Therapeutic …, 2019 - Taylor & Francis
Introduction: Osteoporotic fractures represent a growing burden of mortality, morbidity and
socioeconomic cost to health-care systems worldwide. Osteoporosis is a disease uniquely …

Critical issues and current challenges in osteoporosis and fracture prevention. An overview of unmet needs

WF Lems, HG Raterman - Therapeutic advances in …, 2017 - journals.sagepub.com
Osteoporosis is a silent disease with increasing prevalence due to the global ageing
population. Decreased bone strength and bone quality is the hallmark of osteoporosis which …

[HTML][HTML] Pathophysiology and treatment of osteoporosis: challenges for clinical practice in older people

J Barnsley, G Buckland, PE Chan, A Ong… - Aging clinical and …, 2021 - Springer
Osteoporosis, a common chronic metabolic bone disease is associated with considerable
morbidity and mortality. As the prevalence of osteoporosis increases with age, a paralleled …

[PDF][PDF] Clinical treatments of osteoporosis, how to target co-morbidities

DY Lu, JY Che, Y Shen - EC orthopaedics, 2018 - researchgate.net
The prevalence of osteoporosis in a large population is a social burden globally. Generally,
early diagnosis and treatments can improve the clinical therapeutic outcomes in the clinic …

[图书][B] Handbook of osteoporosis

D Reid - 2011 - books.google.com
Written by a world-recognised expert in the field of osteoporosis, who has published
extensively, and is recognized as a key opinion leader. Aimed at primary care physicians …

Advances in osteoporosis from 1970 to 2018

JC Gallagher - Menopause, 2018 - journals.lww.com
In 1970, there were no drugs under study for osteoporosis. Estrogen was used, but little was
known about the correct dose for preventing bone loss. At that time, fractures were not even …

The osteoporosis treatment gap

EM Curtis, C Cooper, NC Harvey - Osteoporosis treatment: a clinical …, 2021 - Springer
In recent decades, osteoporosis has evolved from being viewed as an inevitable
consequence of ageing to becoming a recognised disease, with a diagnostic definition …

New concepts in the pathogenesis and treatment of osteoporosis

WB Ershler - Frontiers in Biomedicine, 2000 - Springer
Osteoporotic fracture is a major cause of morbidity in older people. For example, in the
United States there are over one million fractures related to diminished bone density each …

Role and evolution of therapeutic options

RW Keen, TD Spector - Osteoporosis International, 1996 - Springer
Conclusions The incidence of osteoporosis has increased over the last 30 years, and is
expected to continue to increase into the next century. Drug treatment for this condition has …