Objective To assess acute cardiorespiratory effects of recruitment manoeuvres in
experimental acute lung injury. Design Experimental study in animal models of acute lung …

Objective: We investigated whether potentially injurious transpulmonary pressure could be
generated by strong spontaneous breathing and exacerbate lung injury even when plateau …

Interventions Twenty isolated sets of normal lungs were perfused (constant flow, 0.3 L/min;
left atrial pressure, 6 mm Hg), ventilated for 20 min (pressure control ventilation, 15 cm H 2 …

Objective: It is known that ventilator-induced lung injury causes increased pulmonary
inflammation. It has been suggested that one of the underlying mechanisms may be strain …

Objectives: To determine the effect on compartmentalization of the tumor necrosis factor
(TNF)-α response in the lung and systemically after ventilation with high peak inspiratory …

Abstract Acute Respiratory Distress Syndrome (ARDS) is a clinical condition secondary to a
variety of insults leading to a severe acute respiratory failure and high mortality in critically ill …

Background Patients with acute respiratory distress syndrome receiving mechanical
ventilation show inhomogeneous lung aeration. Atelectasis during uneven mechanical …

Objective: The role of recruitment maneuvers in mechanical ventilation for patients with the
acute respiratory distress syndrome and acute lung injury remains uncertain in part due to a …

Objective: To investigate the effects of low and high levels of positive end-expiratory
pressure (PEEP), without recruitment maneuvers, during lung protective ventilation in an …

Mechanical ventilation is an often life-saving treatment which unfortunately is not devoid of
risk. In recent years, extensive research has called the attention of physicians to the …