Most eukaryotic mRNAs have a sequence of polyadenylic acid [poly (A)] at their 3′-termini.
These poly (A) tails are normally added post-transcriptionally in the nucleus with an initial …

From the date of its discovery in 1970, the 3'poly (A) tail of eukaryotic mRNA has taken on
the character of a structure in search of a function. Candidate functions favored in those far …

A poly (A) tail is found at the 3 end of nearly every fully processed eukaryotic mRNA and has
been suggested to influence virtually all aspects of mRNA metabolism. Its proposed …

The formation of a eukaryotic mRNA involves a complex series of biochemical events. The
primary transcript is not the messenger RNA, but instead it must first undergo modifications …

Department of Biological Sciences, Columbia University, New York, NY 10027 mRNAs in
eukaryotic cells, as every fresh-man biology student of the last 20 or so years has learned …

Most eukaryotic mRNAs have a poly (A) tail added onto their 3'ends, probably as an early
step in the maturation of the primary transcript. This process involves both cleavage of the …

Labeled adenovirus type 2 nuclear RNA molecules from cells treated with 3′-
deoxyadenosine (3′ dA) were earlier reported to lack polyadenylic acid [poly (A)], but to be …

Messenger RNA molecules in eukaryotic cells are modified at both their 5'and 3'ends, by
a'cap'structure at the former and a poly (A)'tail'at the latter. Formation of the 3'ends of most …

The poly (A) sequences at the 3'end of mRNA and nuclear RNA molecules of mouse
sarcoma and Chinese hamster cells are subject to an elongation process distinct from de …

Three sequences in the vicinity of poly (A) addition sites are conserved among vertebrate
mRNAs. We analyze the effects of single base changes in each position of AAUAAA and in …