The cornea is transparent and avascular, and retention of these characteristics is critical to
maintaining vision clarity. Under normal conditions, wound healing in response to corneal …

The cornea is physiologically avascular. Following a corneal injury, wound healing often
proceeds without neovascularization (NV); however, corneal NV may be induced during …

Corneal scarring due to injury is a leading cause of blindness worldwide and results from
dysregulated inflammation and angiogenesis during wound healing. Here we demonstrate …

Corneal epithelial defects are a common cause of ocular morbidity and can result in corneal
scarring if they do not heal properly. Matrix metalloproteinases (MMPs) are extracellular …

Corneal neovascularization is a significant, sight-threatening, complication of many ocular
surface disorders, but its underlying molecular background is still not fully understood. In the …

Purpose: Matrix metalloproteinase 14 (MMP14) has been shown to be required for corneal
angiogenesis. We hypothesized that the proangiogenic activity of MMP14 may be based on …

Abstract Matrix metalloproteinase‐9 (MMP‐9) is a well‐known regulator and effecter of many
cellular processes including wound healing. In the cornea, either too much or too little MMP …

Objectives:(1) To explore the role and significance of Matrix Metalloproteinase 9 (MMP-9), a
proteolytic enzyme, in various ocular surface diseases of inflammatory, infectious, and …

Matrix metalloproteinases (MMPs) are a family of calcium-dependent, zinc-containing
endoproteinases capable of degrading the extracellular matrix and basement membrane …

Matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) and vascular
endothelial growth factor (VEGF) are all implicated in the development of …