Early pregnancy modulates survival and apoptosis pathways in the corpus luteum in sheep

JH Lee, SK Banu, JA McCracken, JA Arosh - Reproduction, 2016 - rep.bioscientifica.com
The corpus luteum (CL) is a transient endocrine gland. Functional and structural demise of
the CL allows a new estrous cycle. On the other hand, survival of CL and its secretion of …

The effects of luteinizing hormone as a suppression factor for apoptosis in bovine luteal cells in vitro

A Bowolaksono, M Fauzi, AM Sundari… - … in Domestic Animals, 2021 - Wiley Online Library
The fate of the corpus luteum, a transient endocrine gland formed and degraded during an
oestrous cycle, is decided by various physiological factors, such as luteinizing hormone …

Apoptosis, autophagic cell death, and necroptosis: different types of programmed cell death in bovine corpus luteum regression

T Hojo, DJ Skarzynski, K Okuda - Journal of Reproduction and …, 2022 - jstage.jst.go.jp
In mammals, the corpus luteum (CL) is a transient organ that secretes progesterone (P4). In
the absence of pregnancy, the CL undergoes regression (luteolysis), which is a crucial …

Expression of genes associated with apoptosis in the porcine corpus luteum during the oestrous cycle

LM Zorrilla, MA D'Annibale, SE Swing… - … in Domestic Animals, 2013 - Wiley Online Library
Contents The corpus luteum (CL) of the pig lacks luteolytic sensitivity (LS) to prostaglandin
(PG) F‐2α until after day 12 of the oestrous cycle, but the mechanisms underlying this …

Regulatory changes of apoptotic factors in the bovine corpus luteum after induced luteolysis

H Kliem, B Berisha, HHD Meyer… - Molecular …, 2009 - Wiley Online Library
The corpus luteum (CL) offers the opportunity to study not only proliferative, but also
regressive processes. During luteolysis of the CL a sudden death of luteal and endothelial …

Expression of factors associated with apoptosis in the porcine corpus luteum throughout the luteal phase of the estrous cycle and early pregnancy: Their possible …

E Przygrodzka, KJ Witek, MM Kaczmarek… - Theriogenology, 2015 - Elsevier
The studies on the acquisition of luteolytic sensitivity have been focused mainly on
molecular changes induced in the luteal tissue after treatment with exogenous PGF2α or on …

Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle

M Aboelenain, M Kawahara, AZ Balboula… - … of Reproduction and …, 2015 - jstage.jst.go.jp
Corpus luteum (CL) regression is required during the estrous cycle. During CL regression,
luteal cells stop producing progesterone and are degraded by apoptosis. However, the …

Cortisol is a suppressor of apoptosis in bovine corpus luteum

J Komiyama, R Nishimura, HY Lee… - Biology of …, 2008 - academic.oup.com
Glucocorticoid (GC) acts as a modulator of physiological functions in several organs. In the
present study, we examined whether GC suppresses luteolysis in bovine corpus luteum …

Species-related differences in the mechanism of apoptosis during structural luteolysis

N Sugino, K Okuda - Journal of Reproduction and Development, 2007 - jstage.jst.go.jp
Luteolysis is defined as the loss of function and subsequent involution of the luteal structure.
The luteolytic process is usually subdivided, whereby the decline in progesterone is …

Hypoxia promotes luteal cell death in bovine corpus luteum

R Nishimura, J Komiyama, Y Tasaki… - Biology of …, 2008 - academic.oup.com
Low oxygen caused by a decreasing blood supply is known to induce various responses of
cells, including apoptosis. The present study was conducted to examine whether low …