Background & objectives Rosuvastatin calcium (RC) is a potent and competitive synthetic
inhibitor of HMG-CoA reductase used for the treatment of dyslipidemia. Guggulipid obtained …

the side effects of using simvastatin as a blood cholesterol-lowering drug can lead to toxic
myopathy [7].[...] many hyperlipidemia patients prefer to use medicinal plants as an …

Obesity is an important health hazard a known risk factor for several diseases like coronary
heart disease (CHD), angina pectoris hypertension, cardiac failure etc… Recent …

Background: Hypolipidemic activity of gugulipid has been widely described in traditional
literature. Objective: This study was done to evaluate hypolipidemic activity of guggul and …

One of the pathways to reduce cholesterol production in the liver is through the inhibition of
HMG-Coa reductase (HMGCR) by current drugs, statins. However, these have side effects if …

Background: Lipid lowering effect of sumac is investigated in multiple animal studies with
promising results. However, its clinical efficacy is not investigated adequately. This study is …

Background: Dyslipidemia is a major risk factor linking in the direction of the progression of
ischemic heart diseases, which is measured to be the chief principal reason of international …

Purpose Wuzhi capsule (WZ) is a proprietary Chinese medicine prepared from the ethanolic
extract of Schisandra sphenanthera that is commonly used to treat liver injury. Statins are …

Background: Disorders of lipid metabolism are manifested by elevation of the plasma
concentration of the various lipid and lipoprotein fractions and the result, predominantly …

Background: Hypercholesterolemia is a condition of total cholesterol level> 200 mg/dL and
LDL> 130 mg/dL. HMG-CoA (3-hydroxy-3-ethylglutaryl-coenzyme A) reductase is an …