Characterizing and engineering trehalose biosynthesis pathways to improve acetate tolerance in Pseudomonas putida KT2440

ZA Kellermyer, A Bleem, E Kuatsjah, GT Beckham - 2023 - osti.gov
Alkaline pretreatment can depolymerize lignin into a diverse mixture of monomers and
smaller compounds, enabling bioconversion of these compounds to value-added chemicals …

Enhanced production of trehalose in Escherichia coli by homologous expression of otsBA in the presence of the trehalase inhibitor, validamycin A, at high osmolarity

H Li, H Su, SB Kim, YK Chang, SK Hong… - Journal of bioscience …, 2012 - Elsevier
Trehalose production in Escherichia coli DH5α was explored by overexpressing otsBA
operon encoding trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase …

Trends in bacterial trehalose metabolism and significant nodes of metabolic pathway in the direction of trehalose accumulation

R Ruhal, R Kataria, B Choudhury - Microbial Biotechnology, 2013 - Wiley Online Library
The current knowledge of trehalose biosynthesis under stress conditions is incomplete and
needs further research. Since trehalose finds industrial and pharmaceutical applications …

Biochemical and genetic characterization of the pathways for trehalose metabolism in Propionibacterium freudenreichii, and their role in stress response

FS Cardoso, RF Castro, N Borges… - Microbiology, 2007 - microbiologyresearch.org
Propionibacterium freudenreichii accumulates high levels of trehalose, especially in
response to stress. The pathways for trehalose metabolism were characterized, and their …

Trehalose acts as a uridine 5′‐diphosphoglucose‐competitive inhibitor of trehalose 6‐phosphate synthase in Corynebacterium glutamicum

S Oide, M Inui - The FEBS Journal, 2017 - Wiley Online Library
Trehalose is a compatible solute widely distributed in nature. The most prevalent pathway
for its synthesis starts from condensation of glucose 6‐phosphate (Glc6P) and uridine 5 …

Trehalose degradation by Cellvibrio japonicus exhibits no functional redundancy and is solely dependent on the Tre37A enzyme

CA Garcia, JA Narrett, JG Gardner - Applied and Environmental …, 2020 - Am Soc Microbiol
The α-diglucoside trehalose has historically been known as a component of the bacterial
stress response, though it more recently has been studied for its relevance in human gut …

Engineering trehalose synthesis in Lactococcus lactis for improved stress tolerance

AL Carvalho, FS Cardoso, A Bohn… - Applied and …, 2011 - Am Soc Microbiol
Trehalose accumulation is a common cell defense strategy against a variety of stressful
conditions. In particular, our team detected high levels of trehalose in Propionibacterium …

Functional Characterization of Trehalose Biosynthesis Genes from E. coli: An Osmolyte Involved in Stress Tolerance

TC Joseph, LA Rajan, N Thampuran, R James - Molecular biotechnology, 2010 - Springer
Abstract Trehalose (1-α-d-glucopyranosyl-1-α-d-glucopyranoside), a non-reducing
disaccharide is a major compatible solute, which maintains fluidity of membranes and …

[PDF][PDF] Trehalosesynthese in Corynebacterium glutamicum

A Wolf - 2002 - kups.ub.uni-koeln.de
The non-reducing disaccharide trehalose is ubiquitously distributed in nature and commonly
found among prokaryotic and eukaryotic organisms where it is employed as a general stress …

Metabolic Engineering of Corynebacterium glutamicum for Trehalose Overproduction: Role of the TreYZ Trehalose Biosynthetic Pathway

J Carpinelli, R Krämer, E Agosin - Applied and environmental …, 2006 - Am Soc Microbiol
Trehalose has many potential applications in biotechnology and the food industry due to its
protective effect against environmental stress. Our work explores microbiological production …