Chemotaxis of the human pathogen Pseudomonas aeruginosa to the neurotransmitter acetylcholine

MA Matilla, F Velando, A Tajuelo, D Martín-Mora, W Xu… - MBio, 2022 - Am Soc Microbiol
Acetylcholine is a central biological signal molecule present in all kingdoms of life. In
humans, acetylcholine is the primary neurotransmitter of the peripheral nervous system; it …

Systematic mapping of chemoreceptor specificities for Pseudomonas aeruginosa

W Xu, JP Cerna-Vargas, A Tajuelo, A Lozano-Montoya… - Mbio, 2023 - Am Soc Microbiol
The chemotaxis network, one of the most prominent prokaryotic sensory systems, is present
in most motile bacteria and archaea. Although the conserved signaling core of this network …

High-affinity chemotaxis to histamine mediated by the TlpQ chemoreceptor of the human pathogen Pseudomonas aeruginosa

A Corral-Lugo, MA Matilla, D Martín-Mora… - MBio, 2018 - Am Soc Microbiol
Histamine is a key biological signaling molecule. It acts as a neurotransmitter in the central
and peripheral nervous systems and coordinates local inflammatory responses by …

Stimulus sensing and signal processing in bacterial chemotaxis

S Bi, V Sourjik - Current opinion in microbiology, 2018 - Elsevier
Motile bacteria use chemotaxis to migrate towards environments that are favorable for
growth and survival. The signaling pathway that mediates this behavior is largely conserved …

Pseudomonas aeruginosa as a Model To Study Chemosensory Pathway Signaling

MA Matilla, D Martín-Mora, JA Gavira… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Bacteria have evolved a variety of signal transduction mechanisms that generate different
outputs in response to external stimuli. Chemosensory pathways are widespread in bacteria …

[HTML][HTML] The activity of the C4-dicarboxylic acid chemoreceptor of Pseudomonas aeruginosa is controlled by chemoattractants and antagonists

D Martín-Mora, Á Ortega, FJ Pérez-Maldonado… - Scientific reports, 2018 - nature.com
Chemotaxis toward organic acids has been associated with colonization fitness and
virulence and the opportunistic pathogen Pseudomonas aeruginosa exhibits taxis toward …

Identification and characterization of bacterial chemoreceptors using quantitative capillary and gradient plate chemotaxis assays

JA Reyes-Darias, V García, M Rico-Jiménez… - Bio …, 2016 - bio-protocol.org
Bacterial chemotaxis is a motility-based response that biases cell movement toward
beneficial molecules, called attractants, and away from harmful molecules, also known as …

Bacterial chemoreceptors and chemoeffectors

S Bi, L Lai - Cellular and molecular life sciences, 2015 - Springer
Bacteria use chemotaxis signaling pathways to sense environmental changes. Escherichia
coli chemotaxis system represents an ideal model that illustrates fundamental principles of …

Sensory repertoire of bacterial chemoreceptors

Á Ortega, IB Zhulin, T Krell - Microbiology and Molecular Biology …, 2017 - Am Soc Microbiol
Chemoreceptors in bacteria detect a variety of signals and feed this information into
chemosensory pathways that represent a major mode of signal transduction. The five …

Assigning chemoreceptors to chemosensory pathways in Pseudomonas aeruginosa

DR Ortega, AD Fleetwood, T Krell… - Proceedings of the …, 2017 - National Acad Sciences
In contrast to Escherichia coli, a model organism for chemotaxis that has 5 chemoreceptors
and a single chemosensory pathway, Pseudomonas aeruginosa PAO1 has a much more …