Mouse models of lipodystrophy and their significance in understanding fat regulation

JJ Rochford - Current topics in developmental biology, 2014 - Elsevier
Adipose tissue plays a critical role in human metabolic health. This is most dramatically
illustrated by the severe metabolic disease that occurs in syndromes of lipodystrophy where …

Lipodystrophy for the diabetologist—what to look for

N Patni, A Garg - Current diabetes reports, 2022 - Springer
Abstract Purpose of Review Genetic or acquired lipodystrophies are characterized by
selective loss of body fat along with predisposition towards metabolic complications of …

Genetics of lipodystrophy

M Lightbourne, RJ Brown - Endocrinology and Metabolism …, 2017 - endo.theclinics.com
Background The lipodystrophy syndromes are genetic or acquired disorders characterized
by selective loss of adipose tissue that may involve the entire body (generalized) or only …

Approach to the patient with lipodystrophy

LT Fourman, SK Grinspoon - The Journal of Clinical …, 2022 - academic.oup.com
Lipodystrophy constitutes a spectrum of diseases characterized by a generalized or partial
absence of adipose tissue. Underscoring the role of healthy fat in maintenance of metabolic …

Mouse models of lipodystrophy

K Reue, M Péterfy - Current atherosclerosis reports, 2000 - Springer
Lipodystrophies are a group of heterogeneous diseases characterized by the loss of
adipose tissue and by abnormalities of carbohydrate and lipid metabolism, including insulin …

Molecular mechanisms of human lipodystrophies: from adipocyte lipid droplet to oxidative stress and lipotoxicity

C Vigouroux, M Caron-Debarle, C Le Dour… - The international journal …, 2011 - Elsevier
Adipose tissue is now recognized for its major role in the control of energy metabolism and
insulin sensitivity. We review here the human lipodystrophies, that are rare conditions in …

[PDF][PDF] Lipodystrophy: beyond generalization

P Freitas, D Carvalho - Panminerva Med, 2013 - researchgate.net
Genetic and acquired lipodystrophies are disorders of adipose tissue distribution. In this
review we will emphasize its pheno‑type, metabolic and genetic particularities. Special …

Lipodystrophy syndromes

I Hussain, A Garg - Endocrinology and Metabolism Clinics, 2016 - endo.theclinics.com
Lipodystrophies are a group of rare disorders of diverse cause characterized by variable
loss of body fat. The loss of body fat may affect nearly the entire body (generalized), only …

Inherited lipodystrophies and hypertriglyceridemia

V Simha, A Garg - Current opinion in lipidology, 2009 - journals.lww.com
Inherited lipodystrophies and hypertriglyceridemia : Current Opinion in Lipidology Inherited
lipodystrophies and hypertriglyceridemia : Current Opinion in Lipidology Log in or Register …

Lipodystrophies: disorders of adipose tissue biology

A Garg, AK Agarwal - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2009 - Elsevier
The adipocytes synthesize and store triglycerides as lipid droplets surrounded by various
proteins and phospholipids at its surface. Recently, the molecular basis of some of the …