Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
Periodontitis is a common intraoral infection and is inextricably linked to systemic diseases.
Recently, the regulation between host immunologic response and periodontal pathogens …

Gram‐negative periodontal bacteria induce the activation of Toll‐like receptors 2 and 4, and cytokine production in human periodontal ligament cells

Y Sun, R Shu, CL Li, MZ Zhang - Journal of periodontology, 2010 - Wiley Online Library
Background: Periodontitis is a bacterially induced chronic inflammatory disease. Toll‐like
receptors (TLRs), which could recognize microbial pathogens, are important components in …

Porphyromonas gingivalis lipopolysaccharide signaling in gingival fibroblasts–CD14 and Toll-like receptors

PL Wang, K Ohura - Critical Reviews in Oral Biology & …, 2002 - journals.sagepub.com
Periodontal disease is the major cause of adult tooth loss and is commonly characterized by
a chronic inflammation caused by infection of oral bacteria. Porphyromonas gingivalis (P …

Porphyromonas gingivalis Lipopolysaccharide Displays Functionally Diverse Interactions With the Innate Host Defense System

BW Bainbridge, SR Coats… - Annals of …, 2002 - Wiley Online Library
Periodontitis is a bacterially induced chronic inflammatory disease and a major cause of
tooth loss in the world. The tissue damage and alveolar bone resorption characteristic of the …

Intracellular Signaling and Cytokine Induction upon Interactions of Porphyromonas gingivalis Fimbriae with Pattern‐Recognition Receptors

G Hajishengallis, H Sojar, RJ Genco… - Immunological …, 2004 - Taylor & Francis
Toll‐like receptors (TLRs) and other pattern‐recognition receptors (PRRs) of the innate
immune system form functional receptor complexes that recognize and respond to pathogen …

Association between Porphyromonas Gingivalis and systemic diseases: Focus on T cells-mediated adaptive immunity

C Li, R Yu, Y Ding - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
The association between periodontal disease and systemic disease has become a research
hotspot. Porphyromonas gingivalis (P. gingivalis), a crucial periodontal pathogen, affects the …

Variable Cell Responses to P. gingivalis Lipopolysaccharide

L Kocgozlu, R Elkaim, H Tenenbaum… - Journal of dental …, 2009 - journals.sagepub.com
Porphyromonas gingivalis is a major etiological agent of chronic periodontal diseases, the
virulence of which has been attributed to different factors, including lipopolysaccharide …

Identification of signaling pathways in macrophage exposed to Porphyromonas gingivalis or to its purified cell wall components

Q Zhou, S Amar - The Journal of Immunology, 2007 - journals.aai.org
Porphyromonas gingivalis (P. gingivalis) can trigger an inflammatory condition leading to the
destruction of periodontal tissues. However P. gingivalis LPS and its fimbriae (FimA) play …

Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense system

BW Bainbridge, RP Darveau - Acta Odontologica Scandinavica, 2001 - Taylor & Francis
Lipopolysaccharide (LPS) is a key inflammatory mediator. Due to its ability to potently
activate host inflammatory and innate defense responses, it has been proposed to function …

A novel class of lipoprotein lipase-sensitive molecules mediates Toll-like receptor 2 activation by Porphyromonas gingivalis

S Jain, SR Coats, AM Chang… - Infection and Immunity, 2013 - Am Soc Microbiol
Infection by the chronic periodontitis-associated pathogen Porphyromonas gingivalis
activates a Toll-like receptor 2 (TLR2) response that triggers inflammation in the host but …