Signaling Studies of Protein-Peptide Binding on Microelectrode Arrays

K White-Drayton, S Liu, KD Moeller - … Society Meeting Abstracts …, 2021 - iopscience.iop.org
Electrochemical methods provide unique opportunities for non-traditional synthesis and
analytical studies. Using electrochemistry, we are able to synthesize addressable molecular …

Signaling Studies of Protein-Peptide Binding on Microelectrode Arrays

K White - 2022 - openscholarship.wustl.edu
Electrochemical methods provide unique opportunities for non-traditional synthesis and
analytical studies. Using electrochemistry, we are able to synthesize individually …

Organic Electrochemistry and the Use of Microelectrode Arrays to Probe Small-Molecule Protein Interactions

KD Moeller, K White-Drayton, S Liu… - … Meeting Abstracts 241, 2022 - iopscience.iop.org
While electrochemical methods offer many unique opportunities for synthesis, 1 the
relationship does work in both directions. As part of an effort to develop microelectrode …

Microelectrode arrays, electrosynthesis, and the optimization of signaling on an inert, stable surface

K Drayton-White, S Liu, YC Chang… - Beilstein Journal of …, 2022 - beilstein-journals.org
Microelectrode arrays are powerful tools for monitoring binding interactions between small
molecules and biological targets. In most cases, molecules to be studied using such devices …

Microelectrode arrays and the move toward practical applications

KD Moeller, S Uppal, M Graaf, NH Yeh… - … Meeting Abstracts 230, 2016 - iopscience.iop.org
Microelectrode arrays have great potential as a platform for monitoring the interactions
between small molecules and biological receptors in “real-time”. For this reason, we have …

Monitoring “Real-Time” Biological Binding Events on a Microelectrode Array

Y Zhu, KD Moeller - Electrochemical Society Meeting Abstracts …, 2021 - iopscience.iop.org
Because microelectrode arrays contain collections of spatially isolated electrodes that can
each be individually addressed, they provide an intriguing platform for monitoring the activity …

Introduction to microelectrode arrays, the site-selective functionalization of electrode surfaces, and the real-time detection of binding events

MD Graaf, KD Moeller - Langmuir, 2015 - ACS Publications
Microelectrode arrays have great potential as analytical tools because currents can be
independently measured at each electrode in the array. In principle, these currents can be …

Site-selective chemistry and the attachment of peptides to the surface of a microelectrode array

MS Fellet, JL Bartels, B Bi… - Journal of the American …, 2012 - ACS Publications
Peptides have been site-selectively placed on microelectrode arrays with the use of both
thiol-based conjugate additions and Cu (I)-coupling reactions between thiols and aryl …

From molecules to molecular surfaces. Exploiting the interplay between organic synthesis and electrochemistry

Q Jing, KD Moeller - Accounts of chemical research, 2019 - ACS Publications
Conspectus For many years, we have been looking at electrochemistry as a tool for
exploring, developing, and implementing new synthetic methods for the construction of …

Electroorganic synthesis and the construction of addressable molecular surfaces

NH Yeh, Y Zhu, KD Moeller - ChemElectroChem, 2019 - Wiley Online Library
In this Minireview, an electroorganic synthesis approach to the construction of addressable,
complex molecular surfaces is described along with the parameters that guided the …