Recombinant expression of Chlamydia trachomatis major outer membrane protein in E. Coli outer membrane as a substrate for vaccine research
Z Wen, MA Boddicker, RM Kaufhold, P Khandelwal… - BMC microbiology, 2016 - Springer
Background Chlamydia trachomatis is a human pathogen which causes a number of
pathologies, including genital tract infections in women that can result in tubal infertility …
pathologies, including genital tract infections in women that can result in tubal infertility …
Immunization with a MOMP-Based Vaccine Protects Mice against a Pulmonary Chlamydia Challenge and Identifies a Disconnection between Infection and Pathology
Chlamydia pneumoniae is responsible for up to 20% of community acquired pneumonia and
can exacerbate chronic inflammatory diseases. As the majority of infections are either mild …
can exacerbate chronic inflammatory diseases. As the majority of infections are either mild …
Immunogenicity of a vaccine formulated with the Chlamydia trachomatis serovar F, native major outer membrane protein in a nonhuman primate model
To determine the ability of a vaccine formulated with the genital Chlamydia trachomatis,
serovar F, native major outer membrane protein (Ct-F-nMOMP), to induce systemic and …
serovar F, native major outer membrane protein (Ct-F-nMOMP), to induce systemic and …
[HTML][HTML] Induction of protective immunity against Chlamydia muridarum intravaginal infection with the chlamydial immunodominant antigen macrophage infectivity …
C Lu, B Peng, Z Li, L Lei, Z Li, L Chen, Q He… - Microbes and …, 2013 - Elsevier
We previously reported that 5 Chlamydia muridarum antigens reacted with antisera from>
90% mice urogenitally infected with C. muridarum and they are TC0660 (ABC transporter or …
90% mice urogenitally infected with C. muridarum and they are TC0660 (ABC transporter or …
Chlamydia muridarum T-Cell Antigens Formulated with the Adjuvant DDA/TDB Induce Immunity against Infection That Correlates with a High Frequency of Gamma Interferon …
H Yu, X Jiang, C Shen, KP Karunakaran… - Infection and …, 2010 - Am Soc Microbiol
Major impediments to developing a Chlamydia vaccine lie in identifying immunologically
relevant T-cell antigens and delivery in a manner to stimulate protective immunity. Using an …
relevant T-cell antigens and delivery in a manner to stimulate protective immunity. Using an …
Oral immunization with a novel lipid-based adjuvant protects against genital Chlamydia infection
DK Hickey, FE Aldwell, KW Beagley - Vaccine, 2010 - Elsevier
Oral immunization is attractive as a delivery route because it is needle-free and useful for
rapid mass vaccination programs to target pandemics or bioterrorism. This potential has not …
rapid mass vaccination programs to target pandemics or bioterrorism. This potential has not …
PmpG303-311, a Protective Vaccine Epitope That Elicits Persistent Cellular Immune Responses in Chlamydia muridarum-Immune Mice
RM Johnson, H Yu, MS Kerr, JE Slaven… - Infection and …, 2012 - Am Soc Microbiol
Urogenital Chlamydia serovars replicating in reproductive epithelium pose a unique
challenge to host immunity and vaccine development. Previous studies have shown that …
challenge to host immunity and vaccine development. Previous studies have shown that …
Chlamydia pneumoniae Major Outer Membrane Protein Is a Surface-Exposed Antigen That Elicits Antibodies Primarily Directed against Conformation-Dependent …
The major outer membrane protein (MOMP) of Chlamydia trachomatis serovariants is known
to be an immunodominant surface antigen. Moreover, it is known that the C. trachomatis …
to be an immunodominant surface antigen. Moreover, it is known that the C. trachomatis …
The major outer membrane protein of a single Chlamydia trachomatis serovar can possess more than one serovar-specific epitope
BE Batteiger - Infection and immunity, 1996 - Am Soc Microbiol
The major outer membrane proteins (MOMPs) of human Chlamydia trachomatis serovars
exhibit four regions of variable amino acid sequences (VS1 to VS4) harboring serovar …
exhibit four regions of variable amino acid sequences (VS1 to VS4) harboring serovar …
Chlamydia trachomatis-Infected Patients Display Variable Antibody Profiles against the Nine-Member Polymorphic Membrane Protein Family
C Tan, R Hsia, H Shou, CL Haggerty… - Infection and …, 2009 - Am Soc Microbiol
Genomic analysis of the Chlamydiaceae has revealed a multigene family encoding large,
putatively autotransported polymorphic membrane proteins (Pmps) with nine members in …
putatively autotransported polymorphic membrane proteins (Pmps) with nine members in …