While kisspeptin was initially found to function as a metastasis suppressor, after
identification of its receptor KISS1R and their expression profiles in tissues such as the …

Kisspeptin was initially identified as a metastasis suppressor. Shortly after the initial
discovery, a key physiologic role for kisspeptin emerged in the regulation of fertility, with …

Kisspeptin, a neuropeptide hormone, has been firmly established as a key regulator of the
hypothalamic–pituitary–gonadal axis and mammalian reproductive behaviour. In recent …

Kisspeptin is a neuropeptide with a critical role in the function of the hypothalamic–pituitary–
gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in …

Kisspeptin (encoded by the Kiss1 gene) and its receptor, KISS1R (encoded by the Kiss1r
gene), have well-established roles in stimulating reproduction via central actions on …

Abstract Background Kisspeptins, encoded by Kiss1, have emerged as essential regulators
of puberty and reproduction by primarily acting on GnRH neurons, via their canonical …

The neuropeptide kisspeptin regulates reproduction by stimulating gonadotropin-releasing
hormone (GnRH) neurons via the kisspeptin receptor KISS1R. In addition to GnRH neurons …

Aims To investigate the effect of kisspeptin on glucose‐stimulated insulin secretion and
appetite in humans. Materials and methods In 15 healthy men (age: 25.2±1.1 years; BMI …

The hypothalamic-based kisspeptin-signaling system is a major positive regulator of the
neuroendocrine-reproductive axis in mammals. During the last decade, major advances …

Unraveling of the master role of kisspeptins, the products of the KiSS-1 gene, and their
receptor, GPR54, in the control of reproduction has been a major breakthrough in …