Neuroinflammation is closely related to prognosis in ischemic stroke. Microglia are the main
immune cells in the nervous system. Under physiological conditions, microglia participate in …

Inflammatory damage plays a pivotal role in ischemic stroke pathogenesis and may
represent one of the therapeutic targets. Z‐Guggulsterone (Z‐GS), an active component …

Background Ischemic stroke is a major global cause of mortality and permanent disability.
Studies have shown that autophagy is essential to maintain cell homeostasis and inevitably …

Neuroinflammation plays an important role in the pathophysiological process of acute
cerebral infarction, which may aggravate brain injury and hinder neuro-repair. Microglia are …

Brain damage, including blood-brain barrier (BBB) dysfunction, neurological behavior
deficit, cerebral infarction and inflammation, is commonly caused by ischemic-reperfusion …

Microglia-mediated neuroinflammation plays a vital role in the pathogenesis of ischemic
stroke, which serves as a prime target for developing novel therapeutic agent. However …

Global cerebral ischemia (GCI) is a leading cause of mortality worldwide and remains the
primary cause of long-term neurological disability. Astrocyte over-activation and extensive …

Ischemic stroke is one of the leading causes of mortality and disability with documented high
incidence and relapse rate. Accumulating evidence indicates that autophagy participated in …

Summary Aim Ginkgolide B (GB) has shown neuroprotective effect in treating ischemic
stroke, related to its property of anti‐inflammation. Nevertheless, it is unclear whether GB is …

Brain ischemia/reperfusion (I/R) injury is a common pathological process after ischemic
stroke. Pinoresinol diglucoside (PDG) has antioxidation and anti‐inflammation activities …