Aging is a major risk factor for many diseases including metabolic syndrome, cancer,
inflammation, and neurodegeneration. Identifying mechanistic common denominators …

An inverse association between cancer and neurodegeneration is plausible because these
biological processes share several genes and signaling pathways. Whereas uncontrolled …

Abstract Background Brain lesions in Alzheimer's disease (AD) are characterized by Aβ
accumulation, neurofibrillary tangles, and synaptic and neuronal vanishing. According to the …

Long-term memory is believed to be maintained by persistent modifications of synaptic
transmission within the neural circuits that mediate behavior. Thus, long-term potentiation …

The brain represents the primary centre for the regulation and control of all our body
activities, receiving and interpreting sensory impulses and transmitting information to the …

Accumulation of amyloid β peptides (Aβ) in the brain, which is a hallmark of Alzheimer's
disease (AD), is associated with progressive damage to neuronal processes resulting in …

From its discovery as a phosphatidylethanolamine‐binding protein in bovine brain to its
designation as a physiological inhibitor of Raf kinase protein, RKIP has emerged as a critical …

Protein kinase RNA-activated (PKR) induces immune response by sensing viral double-
stranded RNAs (dsRNAs). However, growing evidence suggests that PKR can also be …

Alzheimer's disease (AD) is a neurodegenerative disorder, marked by senile plaques
composed of amyloid-β (Aβ) peptide, neurofibrillary tangles, neuronal loss and …

Ischemic stroke and Alzheimer's disease (AD), despite being distinct disease entities, share
numerous pathophysiological mechanisms such as those mediated by inflammation …