Preclinical and clinical research on the toxic and neurological effects of cassava (Manihot esculenta Crantz) consumption

E Rivadeneyra-Domínguez… - Metabolic brain disease, 2020 - Springer
Abstract Cassava (Manihot esculenta Crantz) is a tropical plant that is used as fresh food,
processed food, or raw material for the preparation of flours with high nutritional value …

Effects of Cassava Juice (Manihot esculenta Crantz) on Renal and Hepatic Function and Motor Impairments in Male Rats

E Rivadeneyra-Domínguez, JE Pérez-Pérez… - Toxins, 2020 - mdpi.com
Cassava (Manihot esculenta Crantz) is a plant that contains neurotoxins such as linamarin
and lotaustraline. Its long-term consumption is associated with neuronal damage and …

Effect of cassava on motor co-ordination and neurotransmitter level in the albino frat

DC Mathangi, V Mohan, A Namasivayam - Food and Chemical toxicology, 1999 - Elsevier
The root of Cassava, a tropical plant, is consumed in the tropics and has been attributed as
the cause for various tropical neuropathies. This study aims to discover the neurotoxic …

Neurological disorders associated with cassava diet: a review of putative etiological mechanisms

B Adamolekun - Metabolic Brain Disease, 2011 - Springer
Tropical ataxic neuropathy (TAN) and epidemic spastic paraparesis (konzo) are two
neurological disorders associated with the consumption of cassava (Manihot esculenta) in …

[PDF][PDF] Rodent Experimental Model of Konzo: Characterization of Motor Impairment and Neurodegeneration after Cassava Neurotoxicity in the Rat

LK David, CW Paul, P Chigeru… - Nigerian Journal of …, 2021 - researchgate.net
Konzo is a motor neuron neurodegenerative disease caused by bitter cassava toxicity that
presents as a non-progressive spastic paraparesis. The ability of bitter cassava to produce …

[PDF][PDF] Model of Konzo disease: Reviewing the effect of bitter cassava neurotoxicity on the motor neurons of cassava-induced konzo disease on Wistar rats

S Enefa, CW Paul, LK David - Saudi Journal of Medicine, 2020 - saudijournals.com
Abstract Introduction: Cassava (Manihot Esculenta) is a staple food in tropical and
subtropical regions in Africa, and is the main source of carbohydrate in these regions …

Neurotoxic effect of linamarin in rats associated with cassava (Manihot esculenta Crantz) consumption

E Rivadeneyra-Domínguez, A Vázquez-Luna… - Food and chemical …, 2013 - Elsevier
Abstract Cassava (Manihot esculenta Crantz) is a plant widely used for food consumption in
different processed products in rural areas of Africa, Asia, and Latin America. Cassava is a …

Food plant chemicals linked with neurological and neurodegenerative disease

PS Spencer, VS Palmer - Advances in neurotoxicology, 2017 - Elsevier
Many plants regularly consumed by humans contain substances that in sufficient doses
have the potential to induce neurological disease. Susceptibility varies but often includes a …

Characterization of cassava (Manihot esculenta Crantz) varieties in Nigeria and Tanzania, and farmers' perception of toxicity of cassava

OSA Oluwole, AO Onabolu, K Mtunda… - Journal of Food …, 2007 - Elsevier
Cassava (Manihot esculenta Crantz) roots in endemic and non-endemic areas for cassava
associated neurological syndromes in Nigeria and Tanzania were characterized for levels of …

[HTML][HTML] Effects of acetone cyanohydrin, a derivative of cassava, on motor activity and kidney and liver function in Wistar rats

E Rivadeneyra-Domínguez, CJ Rosas-Jarquín… - Neurología (English …, 2019 - Elsevier
Introduction Acetone cyanohydrin (ACH) is a toxic substance present in cassava roots
(Manihot esculenta Crantz) which results from enzymatic hydrolysis of linamarin. Long-term …