The Wistar Audiogenic Rat (WAR) strain and its contributions to epileptology and related comorbidities: history and perspectives
N Garcia-Cairasco, EHL Umeoka, JAC de Oliveira - Epilepsy & Behavior, 2017 - Elsevier
In the context of modeling epilepsy and neuropsychiatric comorbidities, we review the Wistar
Audiogenic Rat (WAR), first introduced to the neuroscience international community more …
Audiogenic Rat (WAR), first introduced to the neuroscience international community more …
[HTML][HTML] Wistar audiogenic rats display abnormal behavioral traits associated with artificial selection for seizure susceptibility
GP Castro, D de Castro Medeiros… - Epilepsy & Behavior, 2017 - Elsevier
Accumulating evidence from different animal models has contributed to the understanding of
the bidirectional comorbidity associations between the epileptic condition and behavioral …
the bidirectional comorbidity associations between the epileptic condition and behavioral …
Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs
G De Sarro, E Russo, R Citraro, BS Meldrum - Epilepsy & Behavior, 2017 - Elsevier
This review summarizes the current knowledge about DBA/2 mice and genetically epilepsy-
prone rats (GEPRs) and discusses the contribution of such animal models on the …
prone rats (GEPRs) and discusses the contribution of such animal models on the …
Top common differentially expressed genes in the epileptogenic nucleus of two strains of rodents susceptible to audiogenic seizures: WAR and GASH/Sal
S Damasceno, R Gómez-Nieto… - Frontiers in …, 2020 - frontiersin.org
The Wistar Audiogenic Rat (WAR) and the Genetic Audiogenic Seizure Hamster from
Salamanca (GASH/Sal) strains are audiogenic epilepsy models, in which seizures are …
Salamanca (GASH/Sal) strains are audiogenic epilepsy models, in which seizures are …
Mixed forms of epilepsy in a subpopulation of WAG/Rij rats
IS Midzyanovskaya, GD Kuznetsova, LV Vinogradova… - Epilepsy & Behavior, 2004 - Elsevier
Mixed forms of epilepsy in patients are often refractory. Therefore, animal models of
comorbid convulsive and nonconvulsive seizure are needed for experimental research …
comorbid convulsive and nonconvulsive seizure are needed for experimental research …
The Krushinsky-Molodkina rat strain: The study of audiogenic epilepsy for 65 years
II Poletaeva, NM Surina, ZA Kostina, OV Perepelkina… - Epilepsy & Behavior, 2017 - Elsevier
The more recent history and main experimental data for the Krushinsky–Molodkina (KM)
audiogenic rat strain are presented. The strain selection started in late 1940. Now this strain …
audiogenic rat strain are presented. The strain selection started in late 1940. Now this strain …
Rodent models of audiogenic epilepsy: genetic aspects, advantages, current problems and perspectives
DG Garbuz, AA Davletshin, SA Litvinova, IB Fedotova… - Biomedicines, 2022 - mdpi.com
Animal models of epilepsy are of great importance in epileptology. They are used to study
the mechanisms of epileptogenesis, and search for new genes and regulatory pathways …
the mechanisms of epileptogenesis, and search for new genes and regulatory pathways …
The genetic audiogenic seizure hamster from Salamanca: The GASH: Sal
LJ Muñoz, MM Carballosa-Gautam, K Yanowsky… - Epilepsy & Behavior, 2017 - Elsevier
The hamster has been previously described as a paroxysmal dystonia model, but our strain
is currently recognized as a model of audiogenic seizures (AGS). The original first epileptic …
is currently recognized as a model of audiogenic seizures (AGS). The original first epileptic …
Intrinsic and synaptic properties of hippocampal CA1 pyramidal neurons of the Wistar Audiogenic Rat (WAR) strain, a genetic model of epilepsy
Despite the many studies focusing on epilepsy, a lot of the basic mechanisms underlying
seizure susceptibility are mainly unclear. Here, we studied cellular electrical excitability, as …
seizure susceptibility are mainly unclear. Here, we studied cellular electrical excitability, as …
Transcriptome of the Krushinsky-Molodkina audiogenic rat strain and identification of possible audiogenic epilepsy-associated genes
LN Chuvakova, SY Funikov, AP Rezvykh… - Frontiers in Molecular …, 2021 - frontiersin.org
Audiogenic epilepsy (AE), inherent to several rodent strains is widely studied as a model of
generalized convulsive epilepsy. The molecular mechanisms that determine the …
generalized convulsive epilepsy. The molecular mechanisms that determine the …