C3 glomerulopathy and related disorders in children: etiology-phenotype correlation and outcomes

EKS Wong, KJ Marchbank… - Clinical Journal of the …, 2021 - journals.lww.com
Results Central histology review determined 39 patients with C3 glomerulopathy, 31 with
immune-complex membranoproliferative GN, and ten with immune-complex GN. Patients …

C3 Glomerulopathy

M Riedl, P Thorner, C Licht - Pediatric Nephrology, 2017 - Springer
Recent advances in our understanding of the disease pathology of membranoproliferative
glomerulonephritis has resulted in its re-classification as complement C3 glomerulopathy …

[HTML][HTML] Long-term outcomes of C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis in children

A Kirpalani, N Jawa, WE Smoyer, C Licht… - Kidney International …, 2020 - Elsevier
Introduction The reclassification of membranoproliferative glomerulonephritis (MPGN) into
immune-complex MPGN (IC-MPGN) and C3 glomerulopathy (C3G) has provided insights …

Pediatric C3 glomerulopathy: a 12-year single-center experience

Z Zahir, AS Wani, A Gupta, V Agrawal - Pediatric Nephrology, 2021 - Springer
Background Complement component 3 glomerulopathy (C3G) is a disease with limited data
in children. We aimed to compare childhood C3G cases with adults. We also studied …

Update on C3 glomerulopathy: a complement-mediated disease

F Caravaca-Fontán, L Lucientes, T Cavero, M Praga - Nephron, 2020 - karger.com
Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

Long-term follow-up including extensive complement analysis of a pediatric C3 glomerulopathy cohort

MAHM Michels, KL Wijnsma, RAJ Kurvers, D Westra… - Pediatric …, 2022 - Springer
Abstract Background C3 glomerulopathy (C3G) is a rare kidney disorder characterized by
predominant glomerular depositions of complement C3. C3G can be subdivided into dense …

C3 glomerulopathy: ten years' experience at Mayo Clinic

A Ravindran, FC Fervenza, RJH Smith… - Mayo Clinic …, 2018 - Elsevier
Objective To describe the clinicopathological features, complement abnormalities, triggers,
treatment, and outcomes of C3 glomerulopathy. Patients and Methods A total of 114 patients …

C3 nephritic factor associated with C3 glomerulopathy in children

C Nicolas, V Vuiblet, V Baudouin, MA Macher… - Pediatric …, 2014 - Springer
Abstract Background C3 glomerulopathy (C3G) is characterized by predominant C3
deposits in glomeruli and dysregulation of the alternative pathway of complement. Half of …

Predictors of poor kidney outcome in children with C3 glomerulopathy

AS Pınarbaşı, I Dursun, I Gokce, E Çomak, S Saygılı… - Pediatric …, 2021 - Springer
Abstract Background C3 glomerulopathy (C3G) is characterized by heterogeneous clinical
presentation, outcome, and predominant C3 accumulation in glomeruli without significant …

Evaluation of the children with C3 glomerulopathy

AS Pinarbasi, I Dursun, MH Poyrazoglu… - Saudi Journal of …, 2020 - journals.lww.com
Abstract C3 glomerulopathy (C3G) is a clinical spectrum that presents with a variety of
symptoms, ranging from a mild disease with asymptomatic microhematuria and/or …