182 Flow Characteristics Enhanced by the Compliant Arteries and their effects in Vulnerable Plaque Formation

G da Conceicao Pereira, R Krams - 2015 - heart.bmj.com
Introduction According to the literature, the annual deaths caused by cardiovascular
diseases are dramatically increasing. 1, 2 In addition to the human costs, in the UK alone …

Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: a computational model

F Mac Gabhann, AS Popel - American Journal of …, 2005 - journals.physiology.org
A comprehensive, biophysically accurate, computational model of vascular endothelial
growth factor (VEGF) family member interactions with endothelial cell surface receptors was …

Mechanistic insights into the heterogeneous response to anti‐VEGF treatment in tumors

D Li, SD Finley - Computational and Systems Oncology, 2021 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a strong promoter of angiogenesis in tumors,
and anti‐VEGF treatment, such as a humanized antibody to VEGF, is clinically used as a …

Blood flow and cell‐free layer in microvessels

DA Fedosov, B Caswell, AS Popel… - …, 2010 - Wiley Online Library
Please cite this paper as: Fedosov, Caswell, Popel and Karniadakis (2010). Blood Flow and
Cell‐Free Layer in Microvessels. Microcirculation17 (8), 615–628. Abstract Blood is …

Modeling and simulation of VEGF receptors recruitment in angiogenesis

A Salvadori, V Damioli, C Ravelli… - … Problems in Engineering, 2018 - Wiley Online Library
Angiogenesis, the process of new blood vessel formation from preexisting ones, plays a
pivotal role in tumor growth. Vascular endothelial growth factor receptor‐2 (VEGFR2) is the …

Computational models of VEGF-associated angiogenic processes in cancer

MO Stefanini, AA Qutub… - … Medicine and Biology …, 2012 - ieeexplore.ieee.org
Tumour angiogenesis allows a growing mass of cancer cells to overcome oxygen diffusion
limitation and to increase cell survival. The growth of capillaries from pre-existing blood …

Mathematical models of mass transfer in the vascular walls

K Perktold, M Prosi, P Zunino - … : Modeling and simulation of the circulatory …, 2009 - Springer
As illustrated in detail in chapters 1 and 2, the arterial wall is a heterogeneous structure
consisting of several layers which strongly differ in their thickness and in their biological and …

[HTML][HTML] Simulating cancer: computational models in oncology

H Enderling, KA Rejniak - Frontiers in oncology, 2013 - frontiersin.org
EDITORIAL published: 13 September 2013 doi: 10.3389/fonc. 2013.00233 stem cells in
endometrial cancer. Jain and Jackson ( 4) present a hybrid model that simulates the …

Multiscale modeling of tumor response to vascular endothelial growth factor (VEGF) inhibitor

M Hendrata, J Sudiono - In Silico Biology, 2022 - journals.sagepub.com
Vascular endothelial growth factor (VEGF) has been known as a key mediator of
angiogenesis in cancer. Bevacizumab is anti-VEGF monoclonal antibody that has been …

[HTML][HTML] A hybrid model of tumor growth and angiogenesis: In silico experiments

CM Phillips, EABF Lima, RT Woodall, A Brock… - Plos one, 2020 - journals.plos.org
Tumor associated angiogenesis is the development of new blood vessels in response to
proteins secreted by tumor cells. These new blood vessels allow tumors to continue to grow …