Lung imaging using conventional 1H MRI presents great challenges because of the low
density of lung tissue, lung motion and very fast lung tissue transverse relaxation (typical T2 …

Diffusion magnetic resonance imaging (MRI) is a unique tool that allows studying tissue
structure at a scale that is much smaller than experimentally achievable voxel resolution …

The introduction of hyperpolarized gases (3He and 129Xe) has opened the door to
applications for which gaseous agents are uniquely suited—lung MRI. One of the pulmonary …

Hyperpolarized 3 He gas allows the air spaces of the lungs to be imaged via MRI. Imaging of
restricted diffusion is addressed here, which allows the microstructure of the lung to be …

RATIONALE AND OBJECTIVES: Diffusion magnetic resonance imaging (MRI) with
hyperpolarized 3He gas is a powerful technique for probing the characteristics of the lung …

Lung imaging has traditionally relied on x‐ray methods, since proton MRI is limited to some
extent by low proton density in the lung parenchyma and static field inhomogeneities in the …

The structure and integrity of pulmonary acinar airways and their changes in different
diseases are of great importance and interest to a broad range of physiologists and …

Purpose Parallel imaging can be used to reduce imaging time and to increase the spatial
coverage in hyperpolarized gas magnetic resonance imaging of the lung. In this proof‐of …

We demonstrate a method for simulating restricted diffusion of hyperpolarized gases in lung
airspaces that does not rely on an idealized analytic model of alveolar structure. Instead, the …

In magnetic resonance imaging (MRI), nuclear spins are the source of the image signal. In
the lung, low-proton spin density in alveolar gas and abundant gas-tissue interfaces …